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新加坡非心脏手术后计划性再入院的预测因素:一项为期 2 年的回顾性研究。

Predictors of unplanned hospital readmission after non-cardiac surgery in Singapore: a 2-year retrospective review.

机构信息

Department of Anaesthesia, National University Health System, National University Hospital, Main Building, Level 3 (Near Lift Lobby 1), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.

Department of Anaesthesia, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

出版信息

BMC Surg. 2023 Jul 13;23(1):202. doi: 10.1186/s12893-023-02102-7.

Abstract

INTRODUCTION

Unplanned hospital readmissions after surgery contribute significantly to healthcare costs and potential complications. Identifying predictors of readmission is inherently complex and involves an intricate interplay between medical factors, healthcare system factors and sociocultural factors. Therefore, the aim of this study was to elucidate the predictors of readmissions in an Asian surgical patient population.

METHODS

A two-year single-institution retrospective cohort study of 2744 patients was performed in a university-affiliated tertiary hospital in Singapore, including patients aged 45 and above undergoing intermediate or high-risk non-cardiac surgery. Unadjusted analysis was first performed, followed by multivariable logistic regression.

RESULTS

Two hundred forty-nine patients (9.1%) had unplanned 30-day readmissions. Significant predictors identified from multivariable analysis include: American Society of Anaesthesiologists (ASA) Classification grades 3 to 5 (adjusted OR 1.51, 95% CI 1.10-2.08, p = 0.01), obesity (adjusted OR 1.66, 95% CI 1.18-2.34, p = 0.04), asthma (OR 1.70, 95% CI 1.03-2.81, p = 0.04), renal disease (OR 2.03, 95% CI 1.41-2.92, p < 0.001), malignancy (OR 1.68, 95% CI 1.29-2.37, p < 0.001), chronic obstructive pulmonary disease (OR 2.46, 95% CI 1.19-5.11, p = 0.02), cerebrovascular disease (OR 1.73, 95% CI 1.17-2.58, p < 0.001) and anaemia (OR 1.45, 95% CI 1.07-1.96, p = 0.02).

CONCLUSION

Several significant predictors of unplanned readmissions identified in this Asian surgical population corroborate well with findings from Western studies. Further research will require future prospective studies and development of predictive risk modelling to further address and mitigate this phenomenon.

摘要

简介

手术后计划外的医院再入院对医疗保健成本和潜在并发症有重大影响。识别再入院的预测因素本质上很复杂,涉及医疗因素、医疗保健系统因素和社会文化因素之间的复杂相互作用。因此,本研究的目的是阐明亚洲外科患者人群中再入院的预测因素。

方法

在新加坡的一家大学附属医院进行了一项为期两年的单机构回顾性队列研究,共纳入了 2744 名年龄在 45 岁及以上接受中危或高危非心脏手术的患者。首先进行了未调整分析,然后进行了多变量逻辑回归分析。

结果

249 名患者(9.1%)出现了 30 天计划外再入院。多变量分析确定的显著预测因素包括:美国麻醉师协会(ASA)分级 3 至 5 级(调整后的 OR 1.51,95%CI 1.10-2.08,p=0.01)、肥胖症(调整后的 OR 1.66,95%CI 1.18-2.34,p=0.04)、哮喘(OR 1.70,95%CI 1.03-2.81,p=0.04)、肾脏疾病(OR 2.03,95%CI 1.41-2.92,p<0.001)、恶性肿瘤(OR 1.68,95%CI 1.29-2.37,p<0.001)、慢性阻塞性肺疾病(OR 2.46,95%CI 1.19-5.11,p=0.02)、脑血管疾病(OR 1.73,95%CI 1.17-2.58,p<0.001)和贫血(OR 1.45,95%CI 1.07-1.96,p=0.02)。

结论

在这个亚洲外科人群中确定的几个计划外再入院的显著预测因素与西方研究的发现非常吻合。进一步的研究需要未来的前瞻性研究和预测风险模型的开发,以进一步解决和减轻这一现象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5df/10347775/f2368227474c/12893_2023_2102_Fig1_HTML.jpg

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