Siegal A, Swartz A
Histopathology. 1986 Jul;10(7):761-5. doi: 10.1111/j.1365-2559.1986.tb02531.x.
This paper presents a unique apudoma variant--a malignant carcinoid of mid and lower oesophagus in an elderly man. It was remarkable in the short duration of the clinical symptoms, its rather easy resectability despite its large size and the local perigastric lymph node metastases. On light microscopy, the neoplasm was composed entirely of atypical but uniform round cells lacking argentaffin and argyrophilic staining, arranged in a carcinoid pattern. On electron microscopy, they exhibited dense-core neurosecretory granules.
