Sullivan J L, Packer J T, Bryant M
Arch Pathol Lab Med. 1981 Oct;105(10):515-7.
A primary malignant carcinoid in the testis of a 76-year-old man was studied. The clinical indication was the appearance of extensive, papular cutaneous metastases. A markedly enlarged, indurated left testis was discovered during evaluation of the skin lesions. There were no clinical features of carcinoid syndrome. Histochemically, the tumor cells were argyrophilic but nonreactive to an argentaffin stain. Electron microscopy revealed numerous round, neurosecretory-type granules that ranged from 70 to 300 nm. At the time of autopsy, metastases were found in the heart, lungs, and the opposite testis. Review of the laterature failed to uncover any previous reports of a primary malignant carcinoid in the testis.
对一名76岁男性睾丸原发性恶性类癌进行了研究。临床指征为广泛的丘疹性皮肤转移灶出现。在评估皮肤病变时发现左侧睾丸明显肿大、变硬。无类癌综合征的临床特征。组织化学检查显示,肿瘤细胞嗜银,但对嗜银染色无反应。电子显微镜检查发现大量圆形、神经分泌型颗粒,大小在70至300纳米之间。尸检时,在心脏、肺和对侧睾丸发现了转移灶。查阅文献未发现此前有睾丸原发性恶性类癌的报道。