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护士主导的机械取栓后急性缺血性脑卒中患者快速康复:一项历史对照研究。

Nurse-led rapid rehabilitation following mechanical thrombectomy in patients with acute ischemic stroke: A historical control study.

机构信息

Department of Neurology, West China Hospital, Sichuan University/ West China School of Nursing, Sichuan University, Chengdu, People's Republic of China.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, People's Republic of China.

出版信息

Medicine (Baltimore). 2023 Jul 14;102(28):e34232. doi: 10.1097/MD.0000000000034232.

DOI:10.1097/MD.0000000000034232
PMID:37443519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10344476/
Abstract

The care model composed of a multidisciplinary team is the best model to promote stroke rehabilitation. The objective of this study was to explore the effect of nurse-led rapid rehabilitation on mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS). This study used a non-randomized, historically controlled clinical trial design to compare the efficacy of nurse-led rapid and routine rehabilitation after thrombectomy in patients with ischemic stroke. Treatment outcomes, including hospitalization duration, hospitalization costs, scores on multiple scales at discharge, and clinical outcomes 3 months post-discharge, were assessed and compared between the 2 rehabilitation approaches. Our report is based on the STROBE guidelines. The differences in length of stay in hospital (P = .018), hospitalization expense (P < .001), National Institutes of Health Stroke Scale score (NIHSS) score at discharge (P < .001), modified Rankin scale (MRS) score at discharge (P < .001), and ADL (Activities of Daily Living) score at discharge (P = .156) between the intervention group and the control group were statistically significant. There were statistically significant differences in anxiety/depression (P = .013) and overall quality of life (P = .017) 3 months after discharge. Generalized estimating equation (GEE) analysis showed that interaction effects between group and time were statistically significant for MRS (OR = 0.231, 95% confidence interval: 0.128-0.417, P < .001). The hospitalization time of patients in the intervention group was shortened, and the hospitalization cost was reduced. There were differences in psychological status, and the overall quality of life and improvement of disability status was better.

摘要

由多学科团队组成的护理模式是促进脑卒中康复的最佳模式。本研究旨在探讨护士主导的快速康复对急性缺血性脑卒中(AIS)患者机械取栓(MT)的影响。本研究采用非随机、历史对照临床试验设计,比较了取栓后护士主导的快速康复与常规康复对缺血性脑卒中患者的疗效。评估并比较了两种康复方法的治疗结局,包括住院时间、住院费用、出院时多个量表评分以及出院后 3 个月的临床结局。本报告基于 STROBE 指南。两组间住院时间(P =.018)、住院费用(P <.001)、出院时美国国立卫生研究院卒中量表(NIHSS)评分(P <.001)、出院时改良 Rankin 量表(MRS)评分(P <.001)和日常生活活动(ADL)评分(P =.156)的差异有统计学意义。出院后 3 个月时,焦虑/抑郁(P =.013)和总体生活质量(P =.017)的差异有统计学意义。广义估计方程(GEE)分析显示,MRS 组间和时间间的交互作用有统计学意义(OR = 0.231,95%置信区间:0.128-0.417,P <.001)。干预组患者的住院时间缩短,住院费用降低。心理状态、总体生活质量和残疾改善程度存在差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f213/10344476/2f0a6fcece13/medi-102-e34232-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f213/10344476/2f0a6fcece13/medi-102-e34232-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f213/10344476/2f0a6fcece13/medi-102-e34232-g001.jpg

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