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氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG PET/CT)在同时性乳腺癌和结肠癌患者中的应用价值

Utility of FDG PET/CT in Patient with Synchronous Breast and Colon Cancer.

作者信息

Su I-Lin, Chen Yen-Kung

机构信息

Department of Nuclear Medicine and PET Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan.

School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.

出版信息

Diagnostics (Basel). 2023 Jul 6;13(13):2293. doi: 10.3390/diagnostics13132293.

Abstract

The most common malignancy in women is breast cancer, and the second one is colon cancer. Synchronous breast and colon cancers are rare. Here, we reported a 60-year-old woman with a left breast mass for six months. Biopsy revealed an invasive ductal carcinoma. She underwent 2-[Fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) scan for evaluation of the extent of the disease. FDG PET/CT revealed an advanced left breast cancer with multiple metastases in both regional and distant lymph nodes (in left axilla level I/II, lower paratracheal region, and right lung hilum), bilateral lungs, and axial and proximal appendicular skeletons. An early staged synchronous colon cancer was detected incidentally on FDG PET/CT images. After endoscopic mucosal resection of colon cancer, she received palliative chemotherapy for breast cancer with a marked therapeutic response. The disease status of post-treated breast cancer remained relatively stationary for more than one year. Brain metastasis was noted afterward. Nevertheless, there was no evidence of colon cancer recurrence throughout her breast cancer disease course.

摘要

女性中最常见的恶性肿瘤是乳腺癌,其次是结肠癌。同时发生的乳腺癌和结肠癌很罕见。在此,我们报告一名60岁女性,其左乳肿块已有6个月。活检显示为浸润性导管癌。她接受了2-[氟-18]氟-2-脱氧-D-葡萄糖(FDG)正电子发射断层扫描(PET)/计算机断层扫描(CT)以评估疾病范围。FDG PET/CT显示晚期左乳腺癌,在区域和远处淋巴结(左腋窝I/II级、气管旁下区域和右肺门)、双侧肺以及轴向和近端附属骨骼有多处转移。在FDG PET/CT图像上偶然发现了早期同步结肠癌。结肠癌经内镜黏膜切除术后,她接受了乳腺癌姑息化疗,治疗反应显著。治疗后的乳腺癌疾病状态保持相对稳定超过一年。随后发现有脑转移。然而,在她的乳腺癌病程中没有结肠癌复发的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce06/10341201/68fd04093f62/diagnostics-13-02293-g001.jpg

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