McLoughlin Ramona-M, O'Morain Colm-A
World J Gastroenterol. 2006 Nov 14;12(42):6747-50. doi: 10.3748/wjg.v12.i42.6747.
Colorectal cancer is a major public health burden worldwide. There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use. Most evidence points towards screening with fecal occult blood testing. The immunochemical fecal occult blood tests have a higher sensitivity than the guaiac-based tests. In addition, their automation and haemoglobin quantification allows a threshold for colonoscopy to be selected that can be accommodated within individual health care systems.
结直肠癌是全球主要的公共卫生负担。有明确证据表明筛查可降低结直肠癌死亡率,唯一有争议的问题是使用哪种筛查工具。大多数证据指向采用粪便潜血检测进行筛查。免疫化学粪便潜血检测比基于愈创木脂的检测具有更高的灵敏度。此外,其自动化和血红蛋白定量功能使得能够选择一个适合个体医疗保健系统的结肠镜检查阈值。