Fonseca Mariana Werneck, Trindade Pedro Henrique Esteves, Pinho Renata Haddad, Justo André Augusto, Tomacheuski Rubia Mitalli, Silva Nuno Emanuel de Oliveira Figueiredo da, Gonçalves Heraldo Cesar, Luna Stelio Pacca Loureiro
Department of Surgical Specialties and Anesthesiology, Botucatu Medical School, São Paulo State University (Unesp), Botucatu 18618-687, SP, Brazil.
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University (NCSU), Raleigh, NC 27695, USA.
Animals (Basel). 2023 Jun 28;13(13):2136. doi: 10.3390/ani13132136.
We aimed to develop and validate the Unesp-Botucatu goat acute pain scale (UGAPS). Thirty goats (5 negative controls and 25 submitted to orchiectomy) were filmed for 7 min at the time points 24 h before and 2 h, 3 h (1 h after analgesia), and 24 h after orchiectomy. After content validation, according to an ethogram and literature, four blind observers analyzed the videos randomly to score the UGAPS, repeating the same assessment in 30 days. According to the confirmatory factor analysis, the UGAPS is unidimensional. Intra- and interobserver reliability was very good for all raters (Intraclass correlation coefficient ≥85%). Spearman's correlation between UGAPS versus VAS was 0.85 confirming the criterion validity. Internal consistency was 0.60 for Cronbach's α Cronbach and 0.67 for McDonald's ω. The item-total correlation was acceptable for 80% of the items (0.3-0.7). Specificity and sensitivity based on the cut-off point were 99% and 90%, respectively. The scale was responsive and demonstrated construct validity shown by the increase and decrease of scores after surgery pain and analgesia, respectively. The cut-off point for rescue analgesia is ≥3 of 10, with an area under the curve of 95.27%. The UGAPS presents content, criterion, and construct validities, responsiveness, and reliability to assess postoperative pain in castrated goats.
我们旨在开发并验证圣保罗大学-博图卡图山羊急性疼痛量表(UGAPS)。对30只山羊(5只阴性对照和25只接受去势手术的山羊)在去势手术前24小时、术后2小时、3小时(镇痛后1小时)和24小时的时间点进行7分钟的拍摄。在根据行为图谱和文献进行内容验证后,四名盲法观察者随机分析视频以对UGAPS进行评分,并在30天内重复相同评估。根据验证性因素分析,UGAPS是单维的。所有评分者的观察者内和观察者间信度都非常好(组内相关系数≥85%)。UGAPS与视觉模拟评分法(VAS)之间的斯皮尔曼相关性为0.85,证实了效标效度。克朗巴哈α系数为0.60,麦克唐纳ω系数为0.67。80%的项目的项目-总分相关性可接受(0.3 - 0.7)。基于临界点的特异性和敏感性分别为99%和90%。该量表具有反应性,并分别通过手术疼痛和镇痛后评分的增加和降低证明了结构效度。补救镇痛的临界点为10分中的≥3分,曲线下面积为95.27%。UGAPS在评估去势山羊术后疼痛方面具有内容效度、效标效度和结构效度、反应性及信度。