Feier Catalin Vladut Ionut, Faur Alaviana Monique, Muntean Calin, Blidari Andiana, Contes Oana Elena, Streinu Diana Raluca, Olariu Sorin
First Discipline of Surgery, Department X-Surgery, "Victor Babes" University of Medicine and Pharmacy, 2 E. Murgu Sq., 300041 Timisoara, Romania.
First Surgery Clinic, "Pius Brinzeu" Clinical Emergency Hospital, 300723 Timisoara, Romania.
Healthcare (Basel). 2023 Jun 30;11(13):1903. doi: 10.3390/healthcare11131903.
The aim of this study was to quantify the impact of the COVID-19 pandemic on the surgical treatment of patients with gastric cancer. Data from patients undergoing surgery for gastric cancer during the pandemic were analyzed and the results obtained were compared with the corresponding periods of 2016-2017 and 2018-2019. Various parameters were taken into consideration and their dynamics highlight significant changes in the pandemic year compared with the two pre-pandemic periods. Statistical analysis revealed a marked decrease in the number of surgeries performed during the pandemic ( < 0.001). Severe prognostic factors for gastric cancer, including weight loss and upper gastrointestinal hemorrhage, were associated with an increased number of postoperative fistulas, while emesis was statistically correlated with a more advanced cancer stage ( < 0.011). There was also a reduction in the total duration of hospitalization ( = 0.044) and postoperative hospitalization ( = 0.047); moreover, the mean duration of surgical intervention was higher during the pandemic ( = 0.044). These findings provide evidence for the significant changes in clinical and therapeutic strategies applied to patients undergoing surgery for gastric cancer during the study period. The ongoing pandemic has exerted a substantial and complex impact, the full extent of which remains yet to be fully comprehended.
本研究的目的是量化2019冠状病毒病大流行对胃癌患者外科治疗的影响。分析了大流行期间接受胃癌手术患者的数据，并将所得结果与2016 - 2017年和2018 - 2019年的相应时期进行比较。考虑了各种参数，其动态变化突出了大流行年份与两个大流行前时期相比的显著变化。统计分析显示，大流行期间进行的手术数量显著减少（<0.001）。胃癌的严重预后因素，包括体重减轻和上消化道出血，与术后瘘管数量增加有关，而呕吐与癌症分期更晚在统计学上相关（<0.011）。住院总时长（=0.044）和术后住院时长（=0.047）也有所减少；此外，大流行期间手术干预的平均时长更高（=0.044）。这些发现为研究期间应用于胃癌手术患者的临床和治疗策略的显著变化提供了证据。持续的大流行产生了重大而复杂的影响，其全部范围仍有待充分理解。
