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COVID-19大流行期间甲状腺手术的变化态势:罗马尼亚一家大学医院的四年分析

The Changing Landscape of Thyroid Surgery during the COVID-19 Pandemic: A Four-Year Analysis in a University Hospital in Romania.

作者信息

Feier Catalin Vladut Ionut, Muntean Calin, Faur Alaviana Monique, Blidari Andiana, Contes Oana Elena, Streinu Diana Raluca, Olariu Sorin

机构信息

First Discipline of Surgery, Department X-Surgery, "Victor Babes" University of Medicine and Pharmacy, 2 E. Murgu Sq., 300041 Timisoara, Romania.

First Surgery Clinic, "Pius Brinzeu" Clinical Emergency Hospital, 300723 Timisoara, Romania.

出版信息

Cancers (Basel). 2023 Jun 2;15(11):3032. doi: 10.3390/cancers15113032.

Abstract

The aim of this study was to highlight the changes in the surgical treatment of patients with thyroid pathology over a 4-year period. The dynamics of various parameters during this period at a tertiary University Hospital in Timisoara, Romania were examined. Data from 1339 patients who underwent thyroid surgery between 26 February 2019 and 25 February 2023 were analyzed. The patients were divided into four groups: Pre-COVID-19, C1 (first year of the pandemic), C2 (second year), and C3 (third year). Multiple parameters of the patients were analyzed. Statistical analysis revealed a significant decrease in the number of surgical interventions performed during the first two years of the pandemic ( < 0.001), followed by an increase in subsequent periods (C3). Furthermore, an increase in the size of follicular tumors was observed during this period ( < 0.001), along with an increase in the proportion of patients with T3 and T4 stage in C3. There was also a reduction in the total duration of hospitalization, postoperative hospitalization, and preoperative hospitalization ( < 0.001). Additionally, there was an increase in the duration of the surgical procedure compared to the pre-pandemic period ( < 0.001). Moreover, correlations were observed between the duration of hospitalization and the duration of the surgical procedure (r = 0.147, < 0.001), and between the duration of the surgical procedure and postoperative hospitalization (r = 0.223, < 0.001). These findings confirm the modification of clinical and therapeutic management of patients who underwent thyroid surgery over the past 4 years, with the pandemic generating an impact whose full consequences are not yet fully known.

摘要

本研究的目的是突出甲状腺疾病患者在4年期间手术治疗的变化。对罗马尼亚蒂米什瓦拉一所三级大学医院在此期间各种参数的动态变化进行了研究。分析了2019年2月26日至2023年2月25日期间接受甲状腺手术的1339例患者的数据。患者分为四组:新冠疫情前、C1(疫情第一年)、C2(第二年)和C3(第三年)。对患者的多个参数进行了分析。统计分析显示,疫情前两年进行的手术干预数量显著减少(<0.001),随后各时期(C3)有所增加。此外,在此期间观察到滤泡性肿瘤的大小增加(<0.001),同时C3期T3和T4期患者的比例增加。住院总时长、术后住院时长和术前住院时长也有所减少(<0.001)。此外,与疫情前相比,手术时长有所增加(<0.001)。此外,观察到住院时长与手术时长之间存在相关性(r = 0.147,<0.001),手术时长与术后住院时长之间也存在相关性(r = 0.223,<0.001)。这些发现证实了过去4年接受甲状腺手术患者的临床和治疗管理发生了改变,疫情产生了影响,其全部后果尚未完全知晓。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10252392/44866220182d/cancers-15-03032-g001.jpg

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