Kyuchyuk Selin, Paneva Dilyana, Manolova Nevena, Rashkov Iliya, Karashanova Daniela, Naydenov Mladen, Markova Nadya
Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, Bulgaria.
Institute of Optical Materials and Technologies, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 109, BG-1113 Sofia, Bulgaria.
Materials (Basel). 2023 Jul 7;16(13):4882. doi: 10.3390/ma16134882.
Fibrous materials composed of core-sheath fibers from poly(ethylene oxide) (PEO), beeswax (BW) and 5-nitro-8-hydroxyquinoline (NQ) were prepared via the self-organization of PEO and BW during the single-spinneret electrospinning of a homogeneous blend solution of the partners. Additionally, the application of the same approach enabled the preparation of fibrous materials composed of core-double sheath fibers from PEO, poly(L-lactide) (PLA) and NQ or 5-chloro-7-iodo-8-hydroxyquinoline (CQ), as well as from PEO, poly(ε-caprolactone) (PCL) and NQ. The consecutive selective extraction of BW and of the polyester with hexane and tetrahydrofuran, respectively, evidenced that core-double sheath fibers from PEO/polyester/BW/drug consisted of a PEO core, a polyester inner sheath and a BW outer sheath. In order to evaluate the possibility of the application of fibrous materials from PEO/BW/NQ, PEO/PLA/BW/NQ, PEO/PCL/BW/NQ and PEO/PLA/BW/CQ for plant protection, microbiological studies were performed using both phytopathogenic microorganisms (, and ) and beneficial microorganisms (, and ). It was found that the fibrous materials had anti-bacterial and anti-fungal activity against both phytopathogenic and beneficial microorganisms. This is the first report on the activity of fibrous materials loaded with 8-hydroxyquinoline derivatives not only against phytopathogenic but also against beneficial microorganisms that are of importance in agriculture.
通过在合作伙伴的均相共混溶液的单喷丝头静电纺丝过程中，聚环氧乙烷（PEO）和蜂蜡（BW）的自组装制备了由核壳纤维组成的纤维材料，该核壳纤维由聚环氧乙烷（PEO）、蜂蜡（BW）和5-硝基-8-羟基喹啉（NQ）组成。此外，采用相同方法能够制备由核-双壳纤维组成的纤维材料，这些纤维材料由PEO、聚（L-丙交酯）（PLA）和NQ或5-氯-7-碘-8-羟基喹啉（CQ），以及由PEO、聚（ε-己内酯）（PCL）和NQ组成。分别用己烷和四氢呋喃对BW和聚酯进行连续选择性萃取，证明由PEO/聚酯/BW/药物组成的核-双壳纤维由PEO核、聚酯内壳和BW外壳组成。为了评估PEO/BW/NQ、PEO/PLA/BW/NQ、PEO/PCL/BW/NQ和PEO/PLA/BW/CQ纤维材料用于植物保护的可能性，使用植物病原微生物（、和）和有益微生物（、和）进行了微生物学研究。发现这些纤维材料对植物病原微生物和有益微生物均具有抗菌和抗真菌活性。这是关于负载8-羟基喹啉衍生物的纤维材料不仅对植物病原微生物而且对农业中重要的有益微生物具有活性的首次报道。
