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鼻内急救疗法在癫痫学生癫痫发作丛集期的应用:护士的知识、认知与实践

Use of intranasal rescue therapy for seizure clusters in students with epilepsy: Nurses' knowledge, perceptions, and practice.

作者信息

Santilli Nancy, Dewar Sandra, Guerra Cynthia, Misra Sunita N, Rabinowicz Adrian L, Carrazana Enrique

机构信息

Human Care Systems, 720-84 State St, Boston, MA 02109, United States.

Department of Neurology, Virginia Commonwealth University School of Medicine, 1101 E Marshall St, Richmond, VA 23298-0599, United States.

出版信息

Epilepsy Behav Rep. 2023 Apr 27;22:100604. doi: 10.1016/j.ebr.2023.100604. eCollection 2023.

DOI:10.1016/j.ebr.2023.100604
PMID:37448486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10337358/
Abstract

School nurses play a crucial role in the prompt, appropriate response to epilepsy-related seizure emergencies among students in the school setting. Two intranasal benzodiazepine rescue therapies are now approved and offer potential benefits of being easy to use and socially acceptable. In July 2021, a survey was sent to 49,314 US school nurses to assess knowledge, perceptions, and practice with seizure rescue therapy. Responses were received from 866 (1.8% response rate). Of respondents, 45.7% had used rectal diazepam gel; 9.3%, midazolam nasal spray; and 6.0%, diazepam nasal spray. The majority (58.7%) had not delegated authority to administer rescue therapy, with state/local regulations and lack of willingness of school personnel being the most common barriers to delegation (37.7% and 20.1%, respectively). Additional training of nurses and school staff and progress on delegation policies may help optimize appropriate use of intranasal rescue therapy for seizures and enhance care of students with epilepsy in schools.

摘要

学校护士在学校环境中对学生癫痫相关发作紧急情况做出迅速、恰当的反应方面发挥着关键作用。目前有两种鼻内苯二氮䓬类急救疗法已获批准,它们具有易于使用和社会接受度高的潜在优势。2021年7月,一项调查被发送给49314名美国学校护士,以评估他们对发作急救疗法的知识、认知和实践情况。收到了866份回复(回复率为1.8%)。在受访者中,45.7%使用过直肠地西泮凝胶;9.3%使用过咪达唑仑鼻喷雾剂;6.0%使用过地西泮鼻喷雾剂。大多数(58.7%)没有下放急救疗法的给药权限,州/地方法规和学校工作人员不愿意是下放权限最常见的障碍(分别为37.7%和20.1%)。对护士和学校工作人员进行额外培训以及在授权政策方面取得进展,可能有助于优化鼻内癫痫急救疗法的合理使用,并加强学校中癫痫学生的护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/a3eb43090d2a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/6d090c515fb2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/bc1c4f7f339c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/d289493e639a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/a3eb43090d2a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/6d090c515fb2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/bc1c4f7f339c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/d289493e639a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7f0/10337358/a3eb43090d2a/gr4.jpg

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本文引用的文献

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Epilepsy Behav. 2023 Jan;138:108989. doi: 10.1016/j.yebeh.2022.108989. Epub 2022 Nov 18.
2
Implications of Seizure-Cluster Treatment on Healthcare Utilization: Use of Approved Rescue Medications.癫痫发作簇治疗对医疗资源利用的影响:使用已批准的急救药物。
Neuropsychiatr Dis Treat. 2022 Oct 25;18:2431-2441. doi: 10.2147/NDT.S376104. eCollection 2022.
3
Safety of Diazepam Nasal Spray in Children and Adolescents With Epilepsy: Results From a Long-Term Phase 3 Safety Study.
地西泮鼻喷剂在癫痫儿童和青少年中的安全性:一项长期 3 期安全性研究的结果。
Pediatr Neurol. 2022 Jul;132:50-55. doi: 10.1016/j.pediatrneurol.2022.04.011. Epub 2022 Apr 28.
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Medication Administration Practices in United States' Schools: A Systematic Review and Meta-synthesis.美国学校的药物管理实践:系统评价和元综合。
J Sch Nurs. 2022 Feb;38(1):21-34. doi: 10.1177/10598405211026300. Epub 2021 Jul 5.
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