哪些是与老年男性勃起功能障碍相关的主要危险因素？2436 名巴西老年男性的横断面研究。
What are the Main Risk Factors Associated with Erectile Dysfunction in the Elderly? A Cross-Sectional Study of 2436 Brazilian Elderly Men.
机构信息
Postgrad Program Health Science, Instituto Israelita de Ensino & Pesquisa, São Paulo, SP, Brazil.
Postgrad Program Rehabilitation Science, Universidade Nove Julho, São Paulo, SP, Brazil.
出版信息
Clin Interv Aging. 2023 Jul 8;18:1047-1054. doi: 10.2147/CIA.S405121. eCollection 2023.
BACKGROUND
Erectile dysfunction (ED) is a multifactorial medical disorder often neglected in clinical practice between elderly men, defined as the inability to achieve and/or maintain a penile erection sufficient for satisfactory sexual intercourse and a common clinical entity among men and associated with impaired quality of life and cardiovascular diseases in elderly men. The aim of this study is to evaluate the association between ED and clinical, demographic and behavioral parameters in elderly men.
METHODS
A total of 2436 males aged 60 years and over who participated in the health screening between January 2008 and December 2018 were included in this study. Laboratory exams, clinical and behavior profiles were analyzed. Logistic regression models were used.
RESULTS
Men with ED were older (65.87±5.49 vs. 63.85±4.05 years old. p<0.001), higher prevalence of physical inactivity (23.8 vs. 19%, p = 0.039) and had a higher body mass index (BMI; 28.36±4.06 vs. 27.72±3.89 kg/m. p<0.001) than men without ED. The multivariate model shown that hypertension (p = 0.001), diabetes mellitus (p<0.001), lower urinary tract symptoms (LUTS), depressive symptoms (p<0.001) and age (p<0.001), were strongly associated with ED.
CONCLUSION
The main risk factors associated with ED in elderly men were hypertension, diabetes mellitus, LUTS, depressive symptoms and age.
背景
勃起功能障碍（ED）是一种多因素的医学疾病，在老年男性中常被临床忽视，定义为无法获得和/或维持足以进行满意性交的阴茎勃起，是老年男性中常见的临床实体，与生活质量受损和心血管疾病有关。本研究旨在评估 ED 与老年男性的临床、人口统计学和行为参数之间的关联。
方法
共纳入 2436 名年龄在 60 岁及以上的男性，他们参加了 2008 年 1 月至 2018 年 12 月期间的健康筛查。分析了实验室检查、临床和行为特征。使用逻辑回归模型。
结果
患有 ED 的男性年龄更大（65.87±5.49 岁 vs. 63.85±4.05 岁，p<0.001），体力活动不足的发生率更高（23.8% vs. 19%，p=0.039），并且体重指数（BMI）更高（28.36±4.06 千克/平方米 vs. 27.72±3.89 千克/平方米，p<0.001）。多变量模型显示，高血压（p=0.001）、糖尿病（p<0.001）、下尿路症状（LUTS）、抑郁症状（p<0.001）和年龄（p<0.001）与 ED 密切相关。
结论
与老年男性 ED 相关的主要危险因素是高血压、糖尿病、LUTS、抑郁症状和年龄。
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