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行为相关性勃起功能障碍:系统评价和荟萃分析。

Behavior-Related Erectile Dysfunction: A Systematic Review and Meta-Analysis.

机构信息

Department of Community Health, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.

Department of Community Health, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.

出版信息

J Sex Med. 2021 Jan;18(1):121-143. doi: 10.1016/j.jsxm.2020.09.009. Epub 2020 Nov 20.

DOI:10.1016/j.jsxm.2020.09.009
PMID:33223424
Abstract

BACKGROUND

Erectile dysfunction (ED) is a common problem among men across the world. It is usually multifactorial in origin. Behavioral factors can be related to the development of ED and related to many other chronic diseases. It impacts not only the sexual function but also the psychology and their overall quality of life.

AIM

To determine the association of the behavior factors in relation to ED and to identify the risk and protective factors.

METHOD

A systematic review search based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis was conducted. The primary databases PubMed, PlosOne, Oxford Academic, SCOPUS, and Ovid were accessed using specific keyword searches. Quality of articles was assessed by using Newcastle-Ottawa Assessment Scale according to the study design.

OUTCOME

Evaluation of the relationship between behavioral factors and ED.

RESULTS

24 studies were identified from the 5 databases which met the predetermined criteria. Overall, the study population include adult male age between 18 and 80 years. The sample size of the studies ranges from 101 to the largest sample size of 51,329. Smoking, alcohol, and drugs usage are found to be risk factors for ED. Meanwhile, dietary intake, physical activity, and intimacy are the protective factors for ED.

CLINICAL IMPLICATION

The findings from this review may aid clinicians to aim for early detection of ED by screening their risk factors and providing early treatment. This can also be used to promote awareness to the community on the sexual health and factors that can affect their sexual function.

STRENGTH & LIMITATION: This study looks at all types of behavioral factors that may affect ED; however, there was a substantial heterogeneity detected across the selected study factors. Furthermore, the lack of PROSPERO registration is also a limitation in this study.

CONCLUSION

Overall, smoking, dietary intake, alcohol consumption, drugs, and physical activities are modifiable risk factors for ED in men. Therefore, it is crucial to promote healthy lifestyle and empower men to prevent ED and early detection of ED for early treatment. Sivaratnam L, Selimin DS, Abd Ghani SR, et al. Behavior-Related Erectile Dysfunction: A Systematic Review and Meta-Analysis. J Sex Med 2021;18:121-143.

摘要

背景

勃起功能障碍(ED)是全世界男性常见的问题。它通常是多因素起源的。行为因素可能与 ED 的发展有关,并与许多其他慢性疾病有关。它不仅影响性功能,还影响心理和整体生活质量。

目的

确定与 ED 相关的行为因素的关联,并确定风险和保护因素。

方法

根据系统评价和荟萃分析的首选报告项目进行了系统审查搜索。使用特定的关键字搜索访问了主要数据库 PubMed、PlosOne、Oxford Academic、SCOPUS 和 Ovid。根据研究设计,使用纽卡斯尔-渥太华评估量表评估文章的质量。

结果

从 5 个数据库中确定了 24 项符合预定标准的研究。总体而言,研究人群包括年龄在 18 至 80 岁之间的成年男性。研究的样本量从 101 到最大样本量 51329 不等。吸烟、饮酒和吸毒被发现是 ED 的危险因素。同时,饮食摄入、体育锻炼和亲密关系是 ED 的保护因素。

临床意义

本综述的结果可能有助于临床医生通过筛查其危险因素并提供早期治疗来及早发现 ED。这也可用于向社区宣传性健康以及影响其性功能的因素。

优势与局限性

本研究着眼于所有可能影响 ED 的行为因素;然而,在所选择的研究因素中检测到相当大的异质性。此外,本研究也缺乏 PROSPERO 注册。

结论

总的来说,吸烟、饮食摄入、饮酒、药物和体育活动是男性 ED 的可改变危险因素。因此,促进健康的生活方式并赋予男性预防 ED 和早期发现 ED 以进行早期治疗至关重要。

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