Kaur Jasmeen, Kaur Manmeet
Department of Pathology, AIIMS, Bathinda, Punjab, India.
J Family Med Prim Care. 2023 May;12(5):1009-1011. doi: 10.4103/jfmpc.jfmpc_1591_22. Epub 2023 May 31.
The majority of the tumours occurring in minor salivary glands are malignant with only 18% being benign. Among the benign tumours, pleomorphic adenoma is the most common. Although it presents more commonly in the parotid and submandibular glands, it can occur at any site where salivary glands reside. Only 6.4% of cases of pleomorphic adenoma occur in minor salivary glands, e.g. palate, cheeks, lips, para-pharyngeal space, etc. It occurs in females in the fourth or fifth decade. It presents as an asymptomatic and slow-growing mass. The treatment of choice is wide local excision due to the high rate of recurrence and malignant potential. We present rare case reports of two patients. The first case is of a young 18 years female presenting with recurrent neck (anterior triangle) swelling and the second case is of a 46-year-old female presenting with lower lip swelling. In both cases, it was a slow-growing mass and asymptomatic. Cytological examination of the lesion revealed the diagnosis of pleomorphic adenoma. It was completely excised with no post-operative complication. Pleomorphic adenoma, although a common benign neoplasm of major salivary glands, should always be kept as a possibility at the locations of minor salivary glands. As pleomorphic adenoma can transform into a malignant counterpart, therefore early diagnosis and treatment of the lesion can prevent further complications. The prognosis of pleomorphic adenoma is excellent. However, a close follow-up of the patient is required due to the high rate of recurrence.
小涎腺发生的肿瘤大多为恶性，只有18%为良性。在良性肿瘤中，多形性腺瘤最为常见。虽然它更常见于腮腺和下颌下腺，但可发生于涎腺所在的任何部位。多形性腺瘤仅6.4%发生于小涎腺，如腭部、颊部、唇部、咽旁间隙等。它好发于40或50岁的女性。表现为无症状、生长缓慢的肿块。由于复发率高和有恶变潜能，治疗首选广泛局部切除。我们报告两例罕见病例。第一例为一名18岁年轻女性，表现为颈部（前三角区）反复肿胀，第二例为一名46岁女性，表现为下唇肿胀。两例均为生长缓慢的肿块且无症状。病变的细胞学检查确诊为多形性腺瘤。肿瘤被完整切除，术后无并发症。多形性腺瘤虽然是大涎腺常见的良性肿瘤，但在小涎腺部位也应始终考虑到其可能性。由于多形性腺瘤可转变为恶性肿瘤，因此病变的早期诊断和治疗可预防进一步的并发症。多形性腺瘤的预后良好。然而，由于复发率高，需要对患者进行密切随访。
