Cook W O, Osweiler G D, Anderson T D, Richard J L
J Am Vet Med Assoc. 1986 Jun 15;188(12):1399-402.
Ochratoxicosis was diagnosed in 2 Iowa swine herds. In both cases, clinical signs consisted of increased urination and water consumption. Pale tan kidneys were found in affected pigs at necropsy. Histologic examination of renal tissue from an affected pig revealed diffuse tubular nephrosis and interstitial fibrosis. In both cases, ochratoxin A was detected by thin-layer chromatography in extracts of whole corn and ground complete feed. Ochratoxicosis was reproduced in swine with feed obtained in one of the cases.
在爱荷华州的2个猪群中诊断出赭曲霉毒素中毒。在这两个案例中,临床症状均包括排尿增多和饮水量增加。尸检时在患病猪身上发现肾脏呈淡褐色。对一头患病猪的肾组织进行组织学检查,发现有弥漫性肾小管肾病和间质纤维化。在这两个案例中,通过薄层色谱法在全玉米和粉碎的全价饲料提取物中检测到了赭曲霉毒素A。用其中一个案例中获得的饲料在猪身上再现了赭曲霉毒素中毒。