Fingland R B, Bonagura J D, Myer C W
J Am Vet Med Assoc. 1986 Jul 15;189(2):218-26.
In a retrospective study of 29 dogs with congenital pulmonic stenosis, we evaluated the clinical, radiographic, angiocardiographic, and cardiac catheterization data. Eighteen dogs had no clinical signs of disease and were referred for evaluation of a previously detected cardiac murmur, 5 dogs had congestive right-sided heart failure, and 5 dogs were examined for exercise intolerance or syncope. Dogs with heart failure tended to be older than dogs without clinical signs of heart failure (19.3 months vs 12 months). All dogs had radiographic or electrocardiographic evidence of right ventricular enlargement. Poststenotic dilatation of the main pulmonary artery and apparent pulmonary undercirculation were observed frequently on survey radiographs. Isolated pulmonic valve dysplasia, representing a range of angiographic pulmonic valve abnormalities, was evident in 88% of the available 26 angiographic studies, whereas subvalvular stenosis was uncommon and observed in only 2 dogs. Muscular hypertrophy of the right ventricular infundibulum and supraventricular crest were observed in 96% and 25% of the angiocardiograms, respectively. Poststenotic dilatation of the main pulmonary artery was observed in every dog. A ratio between the width of the main pulmonary artery and the valve annulus was useful in identifying pulmonic stenosis and distinguishing this anomaly from other congenital malformations. The degree of poststenotic dilatation did not appear to be related to the severity of the systolic pressure gradient, which ranged from 20 to 228 mm of Hg (mean, 93 mm of Hg).(ABSTRACT TRUNCATED AT 250 WORDS)
在一项对29只患有先天性肺动脉狭窄犬的回顾性研究中,我们评估了临床、放射学、心血管造影和心导管检查数据。18只犬没有疾病的临床症状,因之前检测到心脏杂音而接受评估;5只犬有右侧充血性心力衰竭;5只犬因运动不耐受或晕厥接受检查。患有心力衰竭的犬往往比没有心力衰竭临床症状的犬年龄大(19.3个月对12个月)。所有犬均有右心室扩大的放射学或心电图证据。在X线平片上经常观察到主肺动脉狭窄后扩张和明显的肺血流减少。在26项可用的心血管造影研究中,88%可见孤立性肺动脉瓣发育异常,表现为一系列心血管造影肺动脉瓣异常,而瓣下狭窄不常见,仅在2只犬中观察到。分别在96%和25%的心血管造影中观察到右心室漏斗部和室上嵴的肌肉肥厚。每只犬均观察到主肺动脉狭窄后扩张。主肺动脉宽度与瓣膜环的比值有助于识别肺动脉狭窄,并将这种异常与其他先天性畸形区分开来。狭窄后扩张程度似乎与收缩压梯度的严重程度无关,收缩压梯度范围为20至228 mmHg(平均93 mmHg)。(摘要截短于250字)