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胃切除术后重度碱性反流性食管炎的治疗体会。

Management Experiences of Post-Gastrectomy Severe Alkaline Reflux Esophagitis.

机构信息

National Oesophagogastric Cancer Centre, Trinity St James Cancer Institute, St James's Hospital, Dublin, Ireland.

Royal College of Surgeons of Ireland, Dublin, Ireland.

出版信息

Am Surg. 2023 Nov;89(11):5012-5016. doi: 10.1177/00031348231189831. Epub 2023 Jul 14.

Abstract

Alkaline reflux esophagitis is a recognized complication of procedures that compromise the lower esophageal sphincter (LES), including gastrectomy. Incidence of reflux is dependent on the reconstructive procedure, with Roux-en-Y (RY) esophagojejunostomy commonly accepted as the optimal method. The authors report their experience of 5 patients who underwent remedial intervention for severe alkaline reflux esophagitis following gastric cancer surgery, over a 6-year period (2014-2020). Primary diagnoses encompassed 4 gastric adenocarcinomas and 1 gastric neuroendocrine tumor. Four patients previously underwent total gastrectomy and 1 subtotal gastrectomy with RY reconstruction. Onset of postoperative reflux symptoms ranged from 2 weeks to 3 years. Failing medical management, all patients underwent jejunojejunal anastomosis and Roux limb length revision with surgical jejunostomy. At follow-up, 4 out of 5 patients had some degree of symptom resolution and one with unresolved symptoms. The authors report our experience of managing this complication following gastrectomy with jejunojejunal anastomosis and Roux limb length revision.

摘要

碱性反流性食管炎是一种公认的食管下括约肌(LES)受损的并发症,包括胃切除术。反流的发生率取决于重建手术,Roux-en-Y(RY)食管空肠吻合术被普遍认为是最佳方法。作者报告了他们在 6 年期间(2014-2020 年)治疗 5 例胃癌手术后严重碱性反流性食管炎的经验。主要诊断包括 4 例胃腺癌和 1 例胃神经内分泌肿瘤。4 例患者先前接受了全胃切除术,1 例接受了 RY 重建的胃大部切除术。术后反流症状的出现时间从 2 周到 3 年不等。在药物治疗失败后,所有患者均接受了空肠空肠吻合术和 Roux 支长度修正术,并进行了手术空肠造口术。在随访中,5 例患者中有 4 例症状有一定程度的缓解,1 例症状未缓解。作者报告了我们在胃切除术后采用空肠空肠吻合术和 Roux 支长度修正术治疗该并发症的经验。

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