Houston Methodist DeBakey Heart and Vascular Center, 6550 Fannin St. Suite 1801 Smith Tower. Houston, TX, 77030, USA.
Curr Cardiol Rep. 2023 Sep;25(9):917-924. doi: 10.1007/s11886-023-01914-6. Epub 2023 Jul 14.
In this review, we summarize the procedural approach and outcomes of venous ethanol infusion in the treatment of ventricular arrhythmias with intramural site of origin.
Coronary venous ethanol infusion has emerged as a novel, safe, and effective adjunctive strategy to radiofrequency ablation of drug refractory ventricular arrhythmias with an intramural origin. Radiofrequency catheter ablation is the first-line treatment for drug refractory ventricular arrythmias. Its success is highly dependent on the ability to reach targeted myocardium. Radiofrequency failures are common in patients with ventricular arrhythmias arising from deep intramural substrates, and those whose origin is in close proximity to vital structures such as coronary arteries or the phrenic nerve. Coronary venous ethanol infusion has emerged as a novel technique that circumvents these limitations.
本文总结了经冠状静脉乙醇注射治疗心室内起源的室性心律失常的方法和结果。
在药物难治性心室内起源的室性心律失常的射频消融治疗中，冠状静脉乙醇注射已成为一种新颖、安全、有效的辅助策略。射频导管消融是药物难治性室性心律失常的一线治疗方法。其成功率高度依赖于到达靶向心肌的能力。对于起源于深部心室内的基质的室性心律失常患者，以及起源于冠状动脉或膈神经等重要结构附近的室性心律失常患者，射频消融失败较为常见。冠状静脉乙醇注射作为一种新技术，克服了这些局限性。
