Blood Transfusion Service, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium; Institute of Experimental and Clinical Research, UCLouvain, 1200 Brussels, Belgium.
Blood Transfusion Service, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium.
Transfus Clin Biol. 2023 Nov;30(4):410-416. doi: 10.1016/j.tracli.2023.06.008. Epub 2023 Jul 13.
Despite major demographic changes, several decisions and initiatives, among which Patient Blood Management, have led to a significant reduction in the transfusion of packed red blood cells (RBCs) in Belgium, as it has been observed in many countries. Unfortunately, not all blood groups were proportionately impacted and shortage in O D-negative RBCs is regularly or chronically observed. The goal of this study was to examine how to optimize the use and the supply of O D-negative blood in our academic hospital.
All blood transfusions performed at Cliniques universitaires Saint-Luc between January 1, 2019 and December 31, 2021 were reviewed. The blood group of the patients was compared with the blood group of the RBCs actually supplied and transfused.
49.823 RBCs transfusions were analyzed. The patients' needs didn't reflect those of a Caucasian population, with an increase of O (47.9%) and B (10.3%) for the ABO blood group, and a quite high proportion of Rr (8.6%) for the Rh blood group. Only two thirds of O D-negative RBCs were transfused to O rr or Rr patients.
The application of PBM and the ethnic imbalance between blood donor and patient populations are two important risk factors for chronic shortages of O D-negative blood. To adapt blood component resources, it is essential to have a complete picture of the real needs of patients according to their blood group profile. Blood donor centers must adapt to the evolving needs of hospitals in order to plan future supplies in a "pull-flow" approach.
尽管人口结构发生了重大变化，但一些决策和举措，包括患者血液管理，导致比利时的红细胞（RBC）输注量显著减少，就像许多国家一样。不幸的是，并非所有血型都受到同等影响，O D-阴性 RBC 的短缺经常或长期存在。本研究的目的是研究如何优化我们学术医院 O D-阴性血液的使用和供应。
回顾了 2019 年 1 月 1 日至 2021 年 12 月 31 日期间在圣吕克大学附属医院进行的所有输血。将患者的血型与实际供应和输注的 RBC 血型进行比较。
分析了 49823 例 RBC 输血。患者的需求与白种人群的需求不符，ABO 血型中 O（47.9%）和 B（10.3%）增加，Rh 血型中 Rr（8.6%）的比例相当高。只有三分之二的 O D-阴性 RBC 输注给 O rr 或 Rr 患者。
PBM 的应用和献血者与患者人群之间的种族失衡是 O D-阴性血液慢性短缺的两个重要危险因素。为了适应血液成分资源，根据患者的血型谱了解患者的实际需求至关重要。献血中心必须适应医院不断变化的需求，以便采用“拉流”方法规划未来的供应。
