Office of Disease Prevention, Office of the Director, National Institutes of Health, 6705 Rockledge Drive, Room 733 MSC 7990, Bethesda, MD, 20892, USA.
Office of Research On Women's Health, Office of the Director, National Institutes of Health, Bethesda, MD, USA.
Prev Sci. 2023 Aug;24(6):1091-1101. doi: 10.1007/s11121-023-01563-9. Epub 2023 Jul 15.
The National Institutes of Health (NIH) Office of Disease Prevention (ODP) sponsors Pathways to Prevention (P2P), an evidence-based scientific workshop program that helps advance prevention research. Each P2P workshop is presided over by an independent expert panel and informed by a systematic evidence review, scientific presentations, and public input. Post-workshop activities include collaborating with federal agency partners to develop an action plan for addressing key research gaps. Primary outcomes of P2P workshops include developing a research agenda and creating or enhancing initiatives to implement the agenda. In 2014, ODP partnered with the NIH Pain Consortium and two NIH institutes to convene "The Role of Opioids in the Treatment of Chronic Pain." This workshop assessed the state-of-the-science on the long-term effectiveness, safety, and harms of opioid use for managing chronic pain. In 2021, ODP initiated an assessment of the outcomes and impact of the Opioids P2P workshop. We applied an evaluation framework and a mixed methods approach encompassing web analytics, bibliometric assessment, grant portfolio analysis, policy assessment, and key informant interviews. Our data showed that the workshop attracted a broad audience, and its published reports had high impact. The workshop also helped inform over 100 new research projects through grants funded by three federal agencies, as well as national legislation and practice guidelines from influential organizations. In sum, the Opioids P2P workshop and follow-up activities have identified gaps in scientific knowledge, informed clinical practice, and catalyzed change on a national level for addressing the prescription opioid crisis.
美国国立卫生研究院（NIH）疾病预防办公室（ODP）赞助了“预防途径”（P2P），这是一个基于证据的科学研讨会计划，旨在推动预防研究。每个 P2P 研讨会都由一个独立的专家小组主持，并通过系统的证据审查、科学演讲和公众意见来提供信息。研讨会后的活动包括与联邦机构合作伙伴合作，制定解决关键研究差距的行动计划。P2P 研讨会的主要成果包括制定研究议程和创建或加强实施该议程的举措。2014 年，ODP 与 NIH 疼痛联合会和两个 NIH 机构合作，召开了“阿片类药物在慢性疼痛治疗中的作用”会议。本次研讨会评估了长期使用阿片类药物治疗慢性疼痛的有效性、安全性和危害的科学现状。2021 年，ODP 开始评估阿片类 P2P 研讨会的结果和影响。我们应用了一个评估框架和一种混合方法，包括网络分析、文献计量评估、资助组合分析、政策评估和关键知情者访谈。我们的数据显示，该研讨会吸引了广泛的受众，其发表的报告具有很高的影响力。该研讨会还通过三个联邦机构资助的 100 多个新项目以及有影响力的组织的国家立法和实践指南，为解决处方类阿片危机提供了信息。总之，阿片类 P2P 研讨会及其后续活动已经确定了科学知识的差距，为临床实践提供了信息，并在国家层面上推动了变革，以应对处方类阿片危机。
