Department of Biomedicine and Prevention, PhD School in Nursing Sciences and Public Health, University of Rome "Tor Vergata", Rome, Italy.
Oncology Unit, John Paul II Hospital of Olbia, Olbia, Italy.
Semin Oncol Nurs. 2023 Aug;39(4):151470. doi: 10.1016/j.soncn.2023.151470. Epub 2023 Jul 16.
This study aims to assess the effects of immersive Virtual Reality in people with cancer undergoing antiblastic therapy, on anxiety, fatigue and pain.
This is a randomized controlled three-arm trial. Seventy-four cancer patients were recruited from a regional hospital in Italy, and randomly allocated into three groups: a Virtual Reality group (n=25), a narrative medicine group (n=25) and a standard care group (n=24). The primary outcome was anxiety. Secondary outcomes included fatigue and pain. The outcomes were evaluated immediately before and after the interventions. The findings showed that anxiety decreased more in the Virtual Reality group (Δpre-post = 6.24, 95% CI 2.578 to 9.902, p=.001, d = 0.63) than in the narrative medicine group, whereas it did not change for those in the standard care group. Fatigue decreased in the Virtual Reality group (Δpre-post = 0.576, 95% CI 0.246 to 0.907, p=.001, d = 0.23), while remaining stable in the narrative medicine group, and increasing in the standard care group. Average levels of pain did not change before and after the intervention [F(1,71) = 1.06, p=.307, ηp2 = .015].
Findings show that virtual reality is effective to reduce anxiety and fatigue in people with cancer undergoing antiblastic therapy.
Virtual Reality can be recommended as an complementary intervention to manage anxiety and fatigue in people with cancer during antiblastic therapy.
ClinicalTrials.gov NCT05629507.
本研究旨在评估沉浸式虚拟现实对接受抗肿瘤治疗的癌症患者的焦虑、疲劳和疼痛的影响。
这是一项随机对照三臂试验。从意大利一家地区医院招募了 74 名癌症患者，并随机分为三组：虚拟现实组（n=25）、叙事医学组（n=25）和标准护理组（n=24）。主要结局是焦虑。次要结局包括疲劳和疼痛。在干预前后立即评估结果。研究结果表明，虚拟现实组的焦虑程度下降更多（Δ预后=6.24，95%CI 2.578 至 9.902，p=.001，d=0.63），而标准护理组则没有变化。虚拟现实组的疲劳程度下降（Δ预后=0.576，95%CI 0.246 至 0.907，p=.001，d=0.23），而叙事医学组保持稳定，标准护理组则增加。干预前后平均疼痛水平没有变化[F(1,71)=1.06，p=.307，ηp2=0.015]。
研究结果表明，虚拟现实对接受抗肿瘤治疗的癌症患者的焦虑和疲劳有治疗效果。
虚拟现实可以作为一种补充干预措施，用于管理接受抗肿瘤治疗的癌症患者的焦虑和疲劳。
ClinicalTrials.gov NCT05629507。
