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肺结核后肺部疾病和慢性阻塞性肺疾病。

Post-tuberculosis lung disease and chronic obstructive pulmonary disease.

机构信息

Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Center for Chronic Airway Diseases, Peking University Health Science Center, Peking University, Beijing 100191, China.

Division of Pulmonology, Department of Medicine, Stellenbosch University & Tygerberg Academic Hospital, Cape Town, South Africa.

出版信息

Chin Med J (Engl). 2023 Aug 20;136(16):1923-1928. doi: 10.1097/CM9.0000000000002771. Epub 2023 Jul 14.

Abstract

The burden of chronic airway diseases, including chronic obstructive pulmonary disease (COPD), continues to increase, especially in low- and middle-income countries. Post-tuberculosis lung disease (PTLD) is characterized by chronic lung changes after the "cure" of pulmonary tuberculosis (TB), which may be associated with the pathogenesis of COPD. However, data on its prevalence, clinical manifestations, computed tomography features, patterns of lung function impairment, and influencing factors are limited. The pathogenic mechanisms underlying PTLD remain to be elucidated. This review summarizes the recent advances in PTLD and TB-associated COPD. Research is urgently needed both for the prevention and management of PTLD.

摘要

慢性气道疾病(包括慢性阻塞性肺疾病,COPD)的负担不断增加,特别是在中低收入国家。肺结核(TB)治愈后发生的肺部病变(PTLD)的特征是慢性肺部改变,其可能与 COPD 的发病机制有关。然而,有关其患病率、临床表现、计算机断层扫描特征、肺功能损害模式和影响因素的数据有限。PTLD 的发病机制仍有待阐明。本综述总结了 PTLD 和与 TB 相关的 COPD 的最新进展。PTLD 的预防和管理都急需开展研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4cb/10431356/a39dd64e1434/cm9-136-1923-g001.jpg

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