Atlas S W, Grossman R I, Goldberg H I, Hackney D B, Bilaniuk L T, Zimmerman R A
J Comput Assist Tomogr. 1986 Sep-Oct;10(5):798-801. doi: 10.1097/00004728-198609000-00017.
High-field magnetic resonance (MR) imaging was performed in three patients with clinically diagnosed acute disseminated encephalomyelitis (ADEM). Contrast enhanced CT was normal in all cases. Magnetic resonance demonstrated multiple foci of demyelination in the brain stem, cerebrum, and cerebellum. Lesions were characteristic, in that they were relatively few in number, frequently present in the brain stem and posterior fossa, nonhemorrhagic, asymmetric, and easily correlated with clinical symptoms and signs. Follow-up MR in one patient who had clinically improved after steroid therapy showed marked resolution of previously documented lesions. Typical MR findings in combination with the appropriate clinical presentation can confirm the diagnosis of ADEM, obviate other more invasive diagnostic tests, identify the extent and sites of involvement, and follow response to therapy.
对3例临床诊断为急性播散性脑脊髓炎（ADEM）的患者进行了高场磁共振（MR）成像检查。所有病例的增强CT均正常。磁共振显示脑干、大脑和小脑有多个脱髓鞘病灶。病变具有特征性，即数量相对较少，常出现在脑干和后颅窝，无出血，不对称，且易于与临床症状和体征相关联。1例经类固醇治疗后临床症状改善的患者进行的随访磁共振显示，先前记录的病灶明显消退。典型的磁共振表现结合适当的临床表现可确诊ADEM，避免其他更具侵入性的诊断检查，确定受累范围和部位，并观察治疗反应。
