Colorectal Unit, King Hussein Medical Center, Royal Medical Services, Amman, Jordan.
Prince Hussein Center for Kidney Diseases, Royal Medical Services, Amman, Jordan.
Pan Afr Med J. 2023 Apr 13;44:170. doi: 10.11604/pamj.2023.44.170.37182. eCollection 2023.
in patients with advanced primary or recurrent gynecologic, urologic, or rectal cancers without metastatic disease, extensive aggressive surgery such as pelvic exenteration may be necessary for curative intent treatment. This study aims to present the initial experience and clinical outcome of curative pelvic exenteration procedures for advanced or recurrent pelvic cancer in our center.
a retrospective cross-sectional study was conducted at the colorectal unit at King Hussein Medical Center in Amman, Jordan, between March 2014 and December 2021. All patients who underwent pelvic exenteration procedures were included in this study. Demographic characteristics, type of procedure, completeness of excision, postoperative complications, morbidity, and mortality were analyzed.
a total of 30 patients underwent thirty-one operations. There were 22 females and eight males with a median age of 55 (range 25-86) years. Twenty-six surgeries were for advanced primary and 5 for recurrent malignancies. Twenty-nine operations were performed for colorectal and 2 for gynecological tumors. There were 19 posterior pelvic exenterations, 2 posterior pelvic exenterations with sacrectomy, and ten total pelvic exenterations. Completeness of tumor excision R0 was observed in 21 specimens, incomplete (R1/R2) in 6 specimens. The overall complication rate was 67.7% and 30-day mortality was 16.7%. Ten (33.3%) patients are disease free at a median follow-up of 22 months.
in our study, pelvic exenteration provides above 40% overall survival at a median follow-up of two years. Gaining experience in this type of procedure, a multidisciplinary approach, careful patients' selection, and preoperative counseling will reduce postoperative morbidity and mortality.
对于患有晚期原发性或复发性妇科、泌尿科或直肠癌症且无转移疾病的患者，为了达到治愈目的，可能需要进行广泛的激进手术，如盆腔廓清术。本研究旨在介绍我们中心治疗晚期或复发性盆腔癌症的根治性盆腔廓清术的初步经验和临床结果。
这是一项在 2014 年 3 月至 2021 年 12 月于约旦安曼侯赛因国王医学中心的结肠直肠科进行的回顾性病例系列研究。本研究纳入了所有接受盆腔廓清术的患者。分析了人口统计学特征、手术类型、切除的完整性、术后并发症、发病率和死亡率。
共有 30 名患者接受了 31 次手术。其中 22 名女性和 8 名男性，中位年龄为 55 岁（范围 25-86 岁）。26 例为晚期原发性肿瘤，5 例为复发性恶性肿瘤。29 例为结直肠肿瘤，2 例为妇科肿瘤。有 19 例为后盆腔廓清术，2 例为后路盆腔廓清术加骶骨切除术，10 例为全盆腔廓清术。21 例标本肿瘤切除完全（R0），6 例标本切除不完全（R1/R2）。总体并发症发生率为 67.7%，30 天死亡率为 16.7%。在中位随访 22 个月时，10 名（33.3%）患者无疾病。
在我们的研究中，盆腔廓清术在中位随访两年时的总体生存率超过 40%。在这种手术类型中获得经验、多学科方法、仔细的患者选择和术前咨询将降低术后发病率和死亡率。
