Charii Hajar, Boudouh Asmae, Mezouari Oumayma, Moueqqit Othman, Kouismi Hatim
Department of Respiratory Diseases, Mohammed VI University Hospital, Oujda, MAR.
Department of Respiratory Diseases, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Cureus. 2023 Jun 12;15(6):e40335. doi: 10.7759/cureus.40335. eCollection 2023 Jun.
Tracheal adenocarcinoma (TAC) is a rare malignancy often characterized by significant delays in diagnosis, often attributed to the non-specific nature of symptoms, leading to subsequent challenges in management. The prognosis remains poor, highlighting the need for early detection and multidisciplinary treatment strategies. Surgical resection is recommended for eligible patients, followed by postsurgical irradiation. However, further research is required to give a better perspective on therapeutic interventions and enhance patient outcomes. This paper reports the case of a 50-year-old male, who presented with dyspnea, hemoptysis, and cough. The computed tomography (CT) revealed an intratracheal tissue mass. The cytological examination and immunocytochemistry confirmed the diagnosis of primary adenocarcinoma in the trachea. The treatment involved silicone tracheobronchial Y-stent followed by adjuvant chemotherapy with carboplatin and paclitaxel, and radiotherapy (60 Gray) with good clinical improvement.
气管腺癌(TAC)是一种罕见的恶性肿瘤,其特点通常是诊断明显延迟,这往往归因于症状的非特异性,从而导致后续治疗面临挑战。其预后仍然很差,这凸显了早期检测和多学科治疗策略的必要性。对于符合条件的患者,建议进行手术切除,术后进行放射治疗。然而,需要进一步研究以更好地了解治疗干预措施并改善患者预后。本文报告了一例50岁男性患者,该患者出现呼吸困难、咯血和咳嗽症状。计算机断层扫描(CT)显示气管内有组织肿块。细胞学检查和免疫细胞化学确诊为原发性气管腺癌。治疗方法包括置入硅酮气管支气管Y形支架,随后使用卡铂和紫杉醇进行辅助化疗,以及放疗(60格雷),临床症状有明显改善。