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一项关于正常、糖尿病和老年皮肤微血管周围面纱细胞的研究。

A study of the veil cells around normal, diabetic, and aged cutaneous microvessels.

作者信息

Braverman I M, Sibley J, Keh-Yen A

出版信息

J Invest Dermatol. 1986 Jan;86(1):57-62. doi: 10.1111/1523-1747.ep12283816.

DOI:10.1111/1523-1747.ep12283816
PMID:3745935
Abstract

The veil cells around normal, diabetic, and aged vessels were reconstructed in 3 dimensions by a computer graphics system from 120-140 serial ultrathin sections. The normal vessel was surrounded by a single layer of veil cells which had a wrinkled and pleated surface. The diabetic vessels were surrounded by 3-6 layers of cellular material produced by increased numbers of veil cells and their associated cytoplasmic sheets. The veil cells around aged vessels appeared to have the same length as young and diabetic veil cells but were underdeveloped in their lateral extensions so that they did not cover the vessel circumferentially as well as did the normal veil cells. Preliminary data suggest that young, diabetic, and aged veil cells have the same metabolic activity per unit area of cytoplasm and are of the same length. The abnormal thickness or thinness of the vascular wall of dermal microvessels appears to be related to the degree of development and numbers of veil cells around the vessels rather than any change in their basic metabolic activity from normal.

摘要

利用计算机图形系统,从120 - 140个连续超薄切片对正常、糖尿病和老龄血管周围的面纱细胞进行了三维重建。正常血管被单层面纱细胞包围,这些细胞表面有皱纹和褶皱。糖尿病血管被3 - 6层由增多的面纱细胞及其相关细胞质片产生的细胞物质包围。老龄血管周围的面纱细胞似乎与年轻和糖尿病面纱细胞长度相同,但侧向延伸发育不良,因此它们不像正常面纱细胞那样能沿血管周向覆盖。初步数据表明,年轻、糖尿病和老龄面纱细胞每单位细胞质面积具有相同的代谢活性,且长度相同。真皮微血管壁厚度的异常或变薄似乎与血管周围面纱细胞的发育程度和数量有关,而非其基本代谢活性相对于正常情况有任何变化。

相似文献

1
A study of the veil cells around normal, diabetic, and aged cutaneous microvessels.一项关于正常、糖尿病和老年皮肤微血管周围面纱细胞的研究。
J Invest Dermatol. 1986 Jan;86(1):57-62. doi: 10.1111/1523-1747.ep12283816.
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Studies in cutaneous aging: II. The microvasculature.皮肤衰老的研究:II. 微血管系统。
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J Invest Dermatol. 1995 Nov;105(5):704-8. doi: 10.1111/1523-1747.ep12324502.
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The veil cell. A shy cell.面纱细胞。一种神秘的细胞。
Arch Dermatol. 1986 Jul;122(7):828-9.
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