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CT 测量的面部轮廓特征反映阻塞性睡眠呼吸暂停患者的上呼吸道形态。

Facial Contour Features Measured on CT Reflects Upper Airway Morphology in Patients With OSA.

机构信息

Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University.

Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University.

出版信息

J Craniofac Surg. 2023;34(8):2399-2404. doi: 10.1097/SCS.0000000000009532. Epub 2023 Jul 18.

DOI:10.1097/SCS.0000000000009532
PMID:37462196
Abstract

OBJECTIVE

To determine facial contour features, measured on computed tomography (CT), related to upper airway morphology in patients with obstructive sleep apnea (OSA); certain phenotype of facial abnormalities implying restriction of craniofacial skeleton and adipose tissue nimiety has predicted the value of the severity of OSA.

MATERIALS AND METHOD

Sixty-four male patients with OSA [apnea-hypopnea index (AHI) ≥10/h] who had upper airway CT were randomly selected to quantitatively measure indicators of facial contour and upper airway structures. Pearson correlation analyses were performed. Partial correlation procedure was used to examine correlations while controlling body mass index (BMI).

RESULTS

Upper airway anatomy can nearly all be reflected in the face, except retroglossal airway. Upper face width can be measured to assess the overall skeletal structures of the airway. Lower face width can be used to represent how much adipose tissue deposited. Hard palate, retropalatal, and hypopharyngeal airways have corresponding face indicators respectively. Midface width is a better predictor of AHI severity and minimum blood oxygen even than neck circumference because it contains the most anatomical information about the airway, including RP airway condition, soft palate length, tongue volume, etc. These correlations persisted even after correction for BMI.

CONCLUSIONS

All anatomical features of the upper airway except retroglossal airway can be reflected in the face, and midface width is the best predictor of AHI severity and minimum blood oxygen, even better than neck circumference and BMI.

摘要

目的

确定与阻塞性睡眠呼吸暂停(OSA)患者上气道形态相关的经计算机断层扫描(CT)测量的面部轮廓特征;某些面部异常的表型暗示颅面骨骼和脂肪组织的限制过多,预测了 OSA 严重程度的价值。

材料与方法

随机选择 64 名患有 OSA(呼吸暂停-低通气指数(AHI)≥10/小时)的男性患者进行上气道 CT 检查,以定量测量面部轮廓和上气道结构的指标。进行 Pearson 相关分析。偏相关程序用于在控制体重指数(BMI)的情况下检查相关性。

结果

除了会厌后气道外,上气道解剖结构几乎都可以反映在面部。上脸宽度可用于评估气道的整体骨骼结构。下脸宽度可用于表示沉积的脂肪组织量。硬腭、会厌后和咽气道分别有相应的面部指标。中面部宽度是 AHI 严重程度和最低血氧的更好预测指标,甚至比颈围更好,因为它包含了关于气道的最多解剖信息,包括 RP 气道状况、软腭长度、舌体积等。即使在校正 BMI 后,这些相关性仍然存在。

结论

除了会厌后气道外,上气道的所有解剖特征都可以反映在面部,中面部宽度是 AHI 严重程度和最低血氧的最佳预测指标,甚至比颈围和 BMI 更好。

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