新型二氨基嘧啶甲酰胺类化合物作为治疗癌症的HPK1抑制剂
Novel Diaminopyrimidine Carboxamides as HPK1 Inhibitors for Treating Cancer.
作者信息
Sabnis Ram W
机构信息
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States.
出版信息
ACS Med Chem Lett. 2023 Jun 21;14(7):899-900. doi: 10.1021/acsmedchemlett.3c00249. eCollection 2023 Jul 13.
Abstract
Provided herein are novel diaminopyrimidine carboxamides as HPK1 inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds.
摘要
本文提供了作为HPK1抑制剂的新型二氨基嘧啶羧酰胺、药物组合物、此类化合物在治疗癌症中的用途以及制备此类化合物的方法。
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