Houser M T, Jahn M F, Kobayashi A, Walburn J
J Pediatr. 1986 Sep;109(3):556-61. doi: 10.1016/s0022-3476(86)80143-3.
We examined the effects of body position and exercise on the random urinary protein/creatinine ratio (Up/Ucr) in healthy adolescents, to provide reference data to be used in a simplified evaluation of proteinuria. Random urine samples were obtained during recumbency and after both ambulation and exercise in 116 subjects. The Up/Ucr was significantly (P less than 0.0001) higher with increasing levels of activity, and was widely variable, especially during the upright and postexercise periods. No sex-related differences in Up/Ucr were noted, except during recumbency, when values were significantly (P less than 0.001) higher in females. The urinary dipstick was found to be less sensitive as a tool to define abnormal degrees of recumbent proteinuria. We conclude that body position and exercise have significant effects on protein excretion, and suggest that the Up/Ucr in recumbent and upright urine samples will be useful in the evaluation of proteinuria.
我们研究了体位和运动对健康青少年随机尿蛋白/肌酐比值（Up/Ucr）的影响，以提供用于蛋白尿简化评估的参考数据。在116名受试者中，分别在卧位、走动后及运动后采集随机尿样。随着活动水平的增加，Up/Ucr显著升高（P<0.0001），且变化很大，尤其是在直立位和运动后期间。除卧位时女性的值显著更高（P<0.001）外，未观察到Up/Ucr存在性别相关差异。发现尿试纸条作为定义卧位蛋白尿异常程度的工具不太敏感。我们得出结论，体位和运动对蛋白质排泄有显著影响，并建议卧位和立位尿样中的Up/Ucr将有助于蛋白尿的评估。
