先天性大叶性肺气肿表现为新生儿呼吸窘迫

Congenital Lobar Emphysema Presenting as Respiratory Distress in a Newborn.

作者信息

Choudhury Sampa, Dubey Suparna, Kumar Ritesh

机构信息

Pathology, Andaman and Nicobar Islands Institute of Medical Sciences (ANIIMS), Port Blair, IND.

Surgery, Andaman and Nicobar Islands Institute of Medical Sciences (ANIIMS), Port Blair, IND.

出版信息

Cureus. 2023 Jun 16;15(6):e40545. doi: 10.7759/cureus.40545. eCollection 2023 Jun.

DOI:10.7759/cureus.40545

PMID:37465796

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10350634/

Abstract

Congenital lobar emphysema (CLE) is a rare developmental malformation that presents as neonatal respiratory distress and can be successfully managed with prompt intervention. Hyperinflation of the affected lobe with mediastinal shift is the characteristic radiological finding. However, the etiology mostly remains unknown. Here, we report a case of CLE that microscopically revealed bronchial cartilaginous hypoplasia as an underlying cause of this malformation.

摘要

先天性肺叶气肿（CLE）是一种罕见的发育畸形，表现为新生儿呼吸窘迫，及时干预可成功治疗。患侧肺叶过度充气并伴有纵隔移位是其典型的影像学表现。然而，其病因大多仍不清楚。在此，我们报告一例先天性肺叶气肿病例，显微镜检查显示支气管软骨发育不全是该畸形的潜在病因。