Mongan P F
J Fam Pract. 1979 May;8(5):939-44.
This is a case presentation and review of an uncommon disorder, tick toxicosis. The history, epidemiology, pathophysiology, and treatment are discussed. This disorder was mentioned in diaries from the early 1800s and has been reported in 18 states and the District of Columbia. A review of 70 cases reveals that the typical patient is a female child who develops leg weakness, irritability, or clumsiness. The exact site at which the toxin induces the paralysis is unknown. Removal of the tick usually reverses the paralysis within hours. Confusing tick toxicosis with other disorders may occur, and death has resulted. This article will remind physicians to consider tick toxicosis when seeing patients with acute ataxia or ascending paralysis and to, perhaps, prevent death from an easily treatable disorder.
这是一例罕见疾病——蜱中毒的病例报告及综述。文中讨论了其病史、流行病学、病理生理学及治疗方法。这种疾病在19世纪早期的日记中就有提及，目前已在美国18个州及哥伦比亚特区有过报道。对70例病例的回顾显示，典型患者为女童，会出现腿部无力、易怒或动作笨拙的症状。毒素诱发麻痹的确切部位尚不清楚。摘除蜱虫通常会在数小时内使麻痹症状逆转。蜱中毒可能会与其他疾病混淆，甚至导致死亡。本文旨在提醒医生，在诊治急性共济失调或上行性麻痹患者时应考虑蜱中毒，或许还能预防因这种易于治疗的疾病导致的死亡。
