儿科放射治疗临床试验中作为危险器官的脊柱管理：QUARTET 的初步经验。
Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience.
机构信息
The European Society for Paediatric Oncology (SIOP Europe), Brussels, Belgium; The European Organisation for Research and Treatment of Cancer (EORTC) Headquarters, Brussels, Belgium; Oncology Department, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj-Napoca, Romania; Radiotherapy Department, Oncology Institute "Prof. Dr. Ion Chiricuta" Cluj-Napoca, Romania.
The European Society for Paediatric Oncology (SIOP Europe), Brussels, Belgium; The European Organisation for Research and Treatment of Cancer (EORTC) Headquarters, Brussels, Belgium; Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
出版信息
Radiother Oncol. 2023 Oct;187:109810. doi: 10.1016/j.radonc.2023.109810. Epub 2023 Jul 17.
Irradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed within QUARTET-affiliated trials. Despite the availability of published consensus guidelines, a high variability in vertebral delineation was observed, with impact on dosimetry.
在青春期前患者中，如果照射不均匀，可能会导致未来的生长畸形，包括脊柱后凸和脊柱侧凸。在 QUARTET 相关试验中对 101 例儿科病例进行了评估，包括椎骨勾画和剂量测定。尽管有已发表的共识指南，但仍观察到椎骨勾画存在很大差异，这对剂量测定有影响。
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