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抗休克裤用于创伤后低血压的前瞻性随机评估。

Prospective randomized evaluation of antishock MAST in post-traumatic hypotension.

作者信息

Mattox K L, Bickell W H, Pepe P E, Mangelsdorff A D

出版信息

J Trauma. 1986 Sep;26(9):779-86. doi: 10.1097/00005373-198609000-00002.

Abstract

During an 18-month period, among 35,000 injured patients presenting to an urban trauma center, more than 3,500 were admitted, and 1,500 underwent surgery on the General Surgical Service. Three hundred fifty-two patients with prehospital systolic blood pressures of less than 90 mm Hg were randomized on an alternate day basis to receive treatment with 'MAST' (163 patients) or 'No-MAST' (189 patients). Age, mechanism of injury, prehospital management times, prehospital trauma scores, prehospital fluids administered, Injury Severity Scores, emergency center treatment, operative protocol, and calculated probability of survival were virtually identical for both groups. Eighty-eight per cent of the injuries were produced by penetrating wounds. The predominant injury area was the abdomen in 40%, the thorax in 37%, and the extremities in 13%. There was no statistically significant difference in evaluation and outcome data between the groups. Within a controlled catchment, only 2.5% of injured patients and 22% of those undergoing operation qualified for prehospital use of MAST. We conclude that for penetrating trauma with prehospital times of 30 minutes or less, MAST provide no advantage with regard to survival, length of hospital stay, or reduced hospital costs.

摘要

在18个月的时间里,在一家城市创伤中心就诊的35000名受伤患者中,超过3500人住院,1500人在普通外科接受手术。352名院前收缩压低于90毫米汞柱的患者被隔日随机分组,分别接受“抗休克裤”治疗(163例)或“不使用抗休克裤”治疗(189例)。两组患者的年龄、受伤机制、院前处理时间、院前创伤评分、院前输注的液体量、损伤严重程度评分、急诊中心治疗、手术方案以及计算得出的生存概率几乎相同。88%的损伤由穿透伤造成。主要损伤部位为腹部(40%)、胸部(37%)和四肢(13%)。两组之间的评估和结果数据没有统计学上的显著差异。在一个可控的区域内,只有2.5%的受伤患者和22%接受手术的患者符合院前使用抗休克裤的条件。我们得出结论,对于院前时间在30分钟或更短的穿透性创伤,抗休克裤在生存、住院时间或降低医院成本方面没有优势。

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