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长时间局灶性癫痫持续状态后脑实质磁共振成像特征的演变：病例研究

Evolution of magnetic resonance imaging features in cerebral parenchyma from prolonged focal status epilepticus: a case study.

作者信息

Lim Sung Chul, Cho Jung Hee, Shon Young-Min

机构信息

Department of Neurology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Encephalitis. 2022 Apr;2(2):58-63. doi: 10.47936/encephalitis.2021.00171. Epub 2021 Dec 8.

DOI:10.47936/encephalitis.2021.00171
PMID:37469653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10295910/
Abstract

It has rarely been documented that permanent alteration of cerebral structures occurs by focal status epilepticus (FSE). We report the case of a 16-year-old boy with FSE in whom serial T1-weighted magnetic resonance volumetry and conventional magnetic resonance imaging were useful for investigating an evolving pattern of morphological changes during and after the FSE, including cortical laminar necrosis (CLN), increased T2 signal intensities, and marked regional atrophy on the corresponding areas. Despite cessation of FSE after adequate medication (combination therapy including clobazam of 1 mg/kg/day), further significant cerebral atrophy was detected at the limited regions where discrete CLN had occurred during the FSE.

摘要

很少有文献记载局灶性癫痫持续状态（FSE）会导致脑结构的永久性改变。我们报告了一例16岁患有FSE的男孩病例，其中系列T1加权磁共振容积测量和传统磁共振成像有助于研究FSE期间及之后形态学变化的演变模式，包括皮质层状坏死（CLN）、T2信号强度增加以及相应区域的明显局部萎缩。尽管在给予适当药物治疗（包括1mg/kg/天氯巴占的联合治疗）后FSE停止，但在FSE期间出现离散CLN的有限区域仍检测到进一步的明显脑萎缩。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08c1/10295910/c407967a3464/encephalitis-2021-00171f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08c1/10295910/d131f4d899cf/encephalitis-2021-00171f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08c1/10295910/c407967a3464/encephalitis-2021-00171f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08c1/10295910/d131f4d899cf/encephalitis-2021-00171f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08c1/10295910/c407967a3464/encephalitis-2021-00171f2.jpg

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本文引用的文献

1
Transient and permanent magnetic resonance imaging abnormalities after complex partial status epilepticus.复杂部分性癫痫持续状态后的短暂性和永久性磁共振成像异常
Epilepsy Behav. 2006 May;8(3):666-71. doi: 10.1016/j.yebeh.2006.01.002. Epub 2006 Feb 28.
2
Reliable manual segmentation of the frontal, parietal, temporal, and occipital lobes on magnetic resonance images of healthy subjects.在健康受试者的磁共振图像上对额叶、顶叶、颞叶和枕叶进行可靠的手动分割。
Brain Res Brain Res Protoc. 2005 Apr;14(3):135-45. doi: 10.1016/j.brainresprot.2004.10.001.
3
Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus.
扩散加权和灌注磁共振成像显示复杂部分性癫痫持续状态时的脑实质变化。
Brain. 2005 Jun;128(Pt 6):1369-76. doi: 10.1093/brain/awh454. Epub 2005 Mar 2.
4
Evolution of MRI changes and development of bilateral hippocampal sclerosis during long lasting generalised status epilepticus.长期全身性癫痫持续状态期间MRI变化的演变及双侧海马硬化的发展
J Neurol Neurosurg Psychiatry. 2004 Jun;75(6):898-900. doi: 10.1136/jnnp.2003.015354.
5
FK506-associated limbic injury following umbilical cord blood transplantation.
Bone Marrow Transplant. 2003 Sep;32(5):523-5. doi: 10.1038/sj.bmt.1704168.
6
Transient MR signal changes in patients with generalized tonicoclonic seizure or status epilepticus: periictal diffusion-weighted imaging.全身强直阵挛性发作或癫痫持续状态患者的短暂磁共振信号变化：发作期弥散加权成像
AJNR Am J Neuroradiol. 2001 Jun-Jul;22(6):1149-60.
7
Volumetry of hippocampus and amygdala with high-resolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories.使用高分辨率MRI和三维分析软件对海马体和杏仁核进行体积测量：尽量减少不同实验室之间的差异。
Cereb Cortex. 2000 Apr;10(4):433-42. doi: 10.1093/cercor/10.4.433.
8
MRI abnormalities associated with partial status epilepticus.与部分性癫痫持续状态相关的磁共振成像异常
Neurology. 1999 Mar 23;52(5):1021-7. doi: 10.1212/wnl.52.5.1021.
9
Serial MR observation of cortical laminar necrosis caused by brain infarction.脑梗死所致皮质层状坏死的磁共振连续观察
Neuroradiology. 1998 Dec;40(12):771-7. doi: 10.1007/s002340050682.
10
Structural consequences of status epilepticus demonstrated with serial magnetic resonance imaging.癫痫持续状态的结构后果通过系列磁共振成像得以显示。
Acta Neurol Scand. 1997 Sep;96(3):127-32. doi: 10.1111/j.1600-0404.1997.tb00253.x.