Deng Chen-Geng, Tang Meng-Yuan, Pan Xue, Liu Zhao-Heng
School of Life Sciences, Beijing University of Chinese Medicine, Beijing 102401, China.
Department of Breast and Thyroid Surgery, China-Japan Friendship Hospital, Beijing 100029, China.
World J Clin Cases. 2023 Jul 6;11(19):4670-4676. doi: 10.12998/wjcc.v11.i19.4670.
Colon cancer (CC) is one of the leading causes of cancer-related morbidity and mortality worldwide. Traditional Chinese medicine (TCM) is widely used in the treatment of various chronic diseases. CC easily metastasizes and results in high morbidity and mortality rates.
A 71-year-old man with a 12-year history of old myocardial infarction and a 7-year history of type 2 diabetes mellitus was diagnosed with CC and underwent right hemicolectomy 1 year ago. Tumor biopsy revealed moderately poorly differentiated adenocarcinoma. Subsequently, chemotherapy with oxaliplatin and paclitaxel was administered. Anastomosis recurrence and pelvic metastasis were noted 37 d later. The patient received eight 21-d cycles of adjuvant chemotherapy with oxaliplatin and capecitabine after recurrence. However, the tumor persisted, and chemotherapy-related liver damage developed gradually. Thus, he was advised to take TCM for the recurrence and pelvic metastasis. The patient's metastatic CC was cured after receiving TCM combined with long-term chemotherapy.
TCM may be an effective adjunct therapy in the treatment of patients with metastatic CC.
结肠癌(CC)是全球癌症相关发病和死亡的主要原因之一。中医(TCM)广泛应用于各种慢性病的治疗。结肠癌易发生转移,导致高发病率和死亡率。
一名71岁男性,有12年陈旧性心肌梗死病史和7年2型糖尿病病史,1年前被诊断为结肠癌并接受了右半结肠切除术。肿瘤活检显示为中低分化腺癌。随后,给予奥沙利铂和紫杉醇化疗。37天后发现吻合口复发和盆腔转移。复发后,患者接受了8个周期、为期21天的奥沙利铂和卡培他滨辅助化疗。然而,肿瘤持续存在,化疗相关的肝损伤逐渐出现。因此,建议他服用中药治疗复发和盆腔转移。该患者在接受中药联合长期化疗后,转移性结肠癌得到治愈。
中药可能是治疗转移性结肠癌患者的一种有效辅助疗法。