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中药联合化疗治疗转移性结肠癌:一例报告

Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report.

作者信息

Deng Chen-Geng, Tang Meng-Yuan, Pan Xue, Liu Zhao-Heng

机构信息

School of Life Sciences, Beijing University of Chinese Medicine, Beijing 102401, China.

Department of Breast and Thyroid Surgery, China-Japan Friendship Hospital, Beijing 100029, China.

出版信息

World J Clin Cases. 2023 Jul 6;11(19):4670-4676. doi: 10.12998/wjcc.v11.i19.4670.

Abstract

BACKGROUND

Colon cancer (CC) is one of the leading causes of cancer-related morbidity and mortality worldwide. Traditional Chinese medicine (TCM) is widely used in the treatment of various chronic diseases. CC easily metastasizes and results in high morbidity and mortality rates.

CASE SUMMARY

A 71-year-old man with a 12-year history of old myocardial infarction and a 7-year history of type 2 diabetes mellitus was diagnosed with CC and underwent right hemicolectomy 1 year ago. Tumor biopsy revealed moderately poorly differentiated adenocarcinoma. Subsequently, chemotherapy with oxaliplatin and paclitaxel was administered. Anastomosis recurrence and pelvic metastasis were noted 37 d later. The patient received eight 21-d cycles of adjuvant chemotherapy with oxaliplatin and capecitabine after recurrence. However, the tumor persisted, and chemotherapy-related liver damage developed gradually. Thus, he was advised to take TCM for the recurrence and pelvic metastasis. The patient's metastatic CC was cured after receiving TCM combined with long-term chemotherapy.

CONCLUSION

TCM may be an effective adjunct therapy in the treatment of patients with metastatic CC.

摘要

背景

结肠癌(CC)是全球癌症相关发病和死亡的主要原因之一。中医(TCM)广泛应用于各种慢性病的治疗。结肠癌易发生转移,导致高发病率和死亡率。

病例摘要

一名71岁男性,有12年陈旧性心肌梗死病史和7年2型糖尿病病史,1年前被诊断为结肠癌并接受了右半结肠切除术。肿瘤活检显示为中低分化腺癌。随后,给予奥沙利铂和紫杉醇化疗。37天后发现吻合口复发和盆腔转移。复发后,患者接受了8个周期、为期21天的奥沙利铂和卡培他滨辅助化疗。然而,肿瘤持续存在,化疗相关的肝损伤逐渐出现。因此,建议他服用中药治疗复发和盆腔转移。该患者在接受中药联合长期化疗后,转移性结肠癌得到治愈。

结论

中药可能是治疗转移性结肠癌患者的一种有效辅助疗法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f4/10353496/0f89e9994901/WJCC-11-4670-g001.jpg

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