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一名既往因静脉注射毒品继发感染性心内膜炎接受三尖瓣手术的患者出现严重三尖瓣反流:病例报告

Severe Tricuspid Regurgitation in a Patient With Previous Tricuspid Valve Surgery for Infective Endocarditis Secondary to Intravenous Drug Use: A Case Report.

作者信息

Khan Zahid, Gul Amresh, Mlawa Gideon

机构信息

Acute Medicine, Mid and South Essex NHS Foundation Trust, Southend-on-Sea, GBR.

Cardiology, Barts Heart Centre, London, GBR.

出版信息

Cureus. 2023 Jun 16;15(6):e40497. doi: 10.7759/cureus.40497. eCollection 2023 Jun.

Abstract

Tricuspid regurgitation (TR) is an important but underappreciated disease in medical practice, and the severity can vary from moderate to severe. Right-sided infective endocarditis (RSIE) is more common in intravenous drug users (IVDUs), and the vast majority of these involve the tricuspid valve (TV). It is worth mentioning that right-sided valves are challenging to scan compared to left-sided valves. The incidence of severe tricuspid regurgitation (TR) immediately post-repair is not tangible, but it is considered to be rare. We present a case of a 47-year-old patient who had previous TV septal leaflet reconstruction using a bovine pericardial patch using 6/0 prolene, and an annuloplasty was performed by placing an annuloplasty ring in 2017 for infective endocarditis. The patient developed moderate to severe tricuspid regurgitation within a few weeks following the surgery. She was readmitted to the hospital four years later with a reduced consciousness level, and a subsequent repeat echocardiogram showed possible tricuspid valve vegetation. In addition, transoesophageal echocardiogram (TOE) demonstrated biventricular dysfunction and severe tricuspid regurgitation, along with moderate to severe mitral regurgitation (MR) that was variable depending on the rate of atrial fibrillation. The patient was not suitable for surgical intervention and was medically managed accordingly.

摘要

三尖瓣反流(TR)在医学实践中是一种重要但未得到充分重视的疾病,其严重程度可从轻度到重度不等。右侧感染性心内膜炎(RSIE)在静脉药物使用者(IVDU)中更为常见,其中绝大多数累及三尖瓣(TV)。值得一提的是,与左侧瓣膜相比,右侧瓣膜的扫描具有挑战性。修复后立即出现严重三尖瓣反流(TR)的发生率并不明确,但被认为很罕见。我们报告一例47岁患者,该患者曾于2017年因感染性心内膜炎使用6/0普理灵缝线用牛心包补片进行三尖瓣隔叶重建,并放置瓣环成形环进行瓣环成形术。患者在手术后几周内出现中度至重度三尖瓣反流。四年后,她因意识水平下降再次入院,随后复查超声心动图显示可能存在三尖瓣赘生物。此外,经食管超声心动图(TOE)显示双心室功能障碍和严重三尖瓣反流,以及中度至重度二尖瓣反流(MR),其程度随房颤发生率而变化。该患者不适合手术干预,因此接受了药物治疗。

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