Lange R, Piazza N, Günther T
Klinik für Herz- und Gefäßchirurgie, Deutsches Herzzentrum München, Technische Universität München, Lazarettstr. 36, 80636, München, Deutschland.
Standort München, Munich Heart Alliance, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), München, Deutschland.
Herz. 2017 Nov;42(7):653-661. doi: 10.1007/s00059-017-4603-0.
Functional tricuspid valve (TV) regurgitation secondary to left heart disease (e.g. mitral insufficiency and stenosis) is observed in 75% of the patients with TV regurgitation and is thus the most common etiology; therefore, the majority of patients who require TV surgery, undergo concomitant mitral and/or aortic valve surgery. Uncorrected moderate and severe TV regurgitation may persist or even worsen after mitral valve surgery, leading to progressive heart failure and death. Patients with moderate to severe TV regurgitation show a 3-year survival rate of 40%. Surgery is indicated in patients with severe TV regurgitation undergoing left-sided valve surgery and in patients with severe isolated primary regurgitation without severe right ventricular (RV) dysfunction. For patients requiring mitral valve surgery, tricuspid valve annuloplasty should be considered even in the absence of significant regurgitation, when severe annular dilatation (≥40 mm or >21 mm/m) is present. Functional TV regurgitation is primarily treated with valve reconstruction which carries a lower perioperative risk than valve replacement. Valve replacement is rarely required. Tricuspid valve repair with ring annuloplasty is associated with better survival and a lower reoperation rate than suture annuloplasty. Long-term results are not available. The severity of the heart insufficiency and comorbidities (e.g. renal failure and liver dysfunction) are the essential determinants of operative mortality and long-term survival. Tricuspid valve reoperations are rarely necessary and associated with a considerable mortality.
继发于左心疾病(如二尖瓣关闭不全和狭窄)的功能性三尖瓣反流在75%的三尖瓣反流患者中可见,因此是最常见的病因;所以,大多数需要进行三尖瓣手术的患者同时接受二尖瓣和/或主动脉瓣手术。二尖瓣手术后,未经纠正的中度和重度三尖瓣反流可能持续存在甚至加重,导致进行性心力衰竭和死亡。中度至重度三尖瓣反流患者的3年生存率为40%。对于接受左侧瓣膜手术的重度三尖瓣反流患者以及无严重右心室功能障碍的重度孤立性原发性反流患者,建议进行手术。对于需要进行二尖瓣手术的患者,即使不存在明显反流,但存在严重瓣环扩张(≥40毫米或>21毫米/米)时,也应考虑三尖瓣瓣环成形术。功能性三尖瓣反流主要通过瓣膜重建进行治疗,其围手术期风险低于瓣膜置换术。很少需要进行瓣膜置换。与缝合瓣环成形术相比,采用带环瓣环成形术进行三尖瓣修复可提高生存率并降低再次手术率。尚无长期结果。心力衰竭的严重程度和合并症(如肾衰竭和肝功能障碍)是手术死亡率和长期生存率的重要决定因素。三尖瓣再次手术很少需要,且死亡率相当高。