Arkin H, Holmes K R, Chen M M, Bottje W G
J Biomech Eng. 1986 Aug;108(3):208-14. doi: 10.1115/1.3138604.
Presented here is a theoretical analysis of the recently developed thermal pulse decay (TPD) method for a simultaneous measurement of local tissue conductivity and blood perfusion rate. The paper describes the theoretical model upon which the TPD method is based and details its capabilities and limitations. The theoretical aspects that affected the development of the measurement protocol are also discussed. The performance of the method is demonstrated with an experimental example which compares the measurements of local kidney blood perfusion rates made using the TPD method with the total renal blood flow obtained coincidentally using a blood flowmeter, in an anesthetized dog.
本文介绍了最近开发的热脉冲衰减（TPD）方法的理论分析，该方法用于同时测量局部组织电导率和血流灌注率。本文描述了TPD方法所基于的理论模型，并详细阐述了其功能和局限性。还讨论了影响测量方案开发的理论方面。通过一个实验示例展示了该方法的性能，该实验比较了在一只麻醉犬身上使用TPD方法测量的局部肾脏血流灌注率与同时使用血流计获得的总肾血流量。
