Anderson G T, Valvano J W
Department of Electronics and Instrumentation, University of Arkansas at Little Rock 72204.
J Biomech Eng. 1994 Feb;116(1):71-8. doi: 10.1115/1.2895707.
A small artery model (SAM) for self-heated thermistor measurements of perfusion in the canine kidney is developed based on the anatomy of the cortex vasculature. In this model interlobular arteries and veins play a dominant role in the heat transfer due to blood flow. Effective thermal conductivity, kss, is calculated from steady state thermistor measurements of heat transfer in the kidney cortex. This small artery and vein model of perfusion correctly indicates the shape of the measured kss versus perfusion curve. It also correctly predicts that the sinusoidal response of the thermistor can be used to measure intrinsic tissue conductivity, km, in perfused tissue. Although this model is specific for the canine kidney cortex, the modeling approach is applicable for a wide variety of biologic tissues.
基于肾皮质脉管系统的解剖结构，开发了一种用于自热式热敏电阻测量犬肾灌注的小动脉模型（SAM）。在该模型中，小叶间动脉和静脉在因血流导致的热传递中起主导作用。有效热导率kss是通过对肾皮质热传递的稳态热敏电阻测量来计算的。这种灌注的小动脉和静脉模型正确地表明了测量的kss与灌注曲线的形状。它还正确地预测了热敏电阻的正弦响应可用于测量灌注组织中的固有组织电导率km。尽管该模型是针对犬肾皮质的，但建模方法适用于多种生物组织。
