Heilongjiang University of Chinese Medicine, Harbin, China.
Department of Acupuncture and Moxibustion, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Medicine (Baltimore). 2023 Jul 21;102(29):e34086. doi: 10.1097/MD.0000000000034086.
The network meta-analysis was used to evaluate the efficacy of acupuncture combined with other therapies in the treatment of post stroke cognitive impairment (PSCI).
The China National Knowledge Infrastructure, Wanfang DATA, Vip Chinese Periodic Service Platform, PUBMED, Cochrane Library, Web of Science, and Embase were searched for randomized controlled trials (RCTs) published before March 18, 2023. Two researchers independently reviewed articles and extracted data, and then qualified papers were included in the study. STATA 14.0 was used for network meta-analysis.
A total of 29 articles including 2241 patients were included in this study. The treatment of the intervention group includes acupuncture combined with traditional Chinese medicine prescriptions (TCMP), acupuncture combined with hyperbaric oxygen (HBO), acupuncture combined with repetitive transcranial magnetic stimulation (rTMS), acupuncture combined with cognitive rehabilitation (CR), acupuncture combined with donepezil. The intervention of the control group includes acupuncture, HBO, rTMS, CR, TCMP, and donepezil. In terms of improving the score of Minimum Mental State Examination (MMSE), acupuncture combined with TCMP was most likely to be the best treatment (P < .05). In terms of improving the score of Montreal Cognitive Assessment (MoCA), acupuncture combined with TCMP was most likely to be the best treatment (P < .05). In terms of improving the total effective rate of clinical treatment, acupuncture combined with rTMS was most likely to be the best treatment (P < .05).
Acupuncture combined with TCMP may be the best treatment method among all of the above treatments for PSCI.
采用网状 Meta 分析评价针刺联合其他疗法治疗脑卒中后认知障碍(PSCI)的疗效。
计算机检索中国知网、万方数据、维普中文期刊服务平台、PubMed、Cochrane 图书馆、Web of Science、Embase 数据库,搜集针刺联合其他疗法治疗 PSCI 的随机对照试验(RCT),检索时限均为建库至 2023 年 3 月 18 日。由 2 位研究者独立筛选文献、提取资料,并进行方法学质量评价后,采用 STATA 14.0 软件进行网状 Meta 分析。
共纳入 29 篇文献 2241 例患者。干预组治疗措施包括针刺联合中药方剂、针刺联合高压氧、针刺联合重复经颅磁刺激、针刺联合认知康复、针刺联合多奈哌齐;对照组治疗措施包括针刺、高压氧、重复经颅磁刺激、认知康复、中药方剂、多奈哌齐。在改善简易精神状态检查量表(MMSE)评分方面,针刺联合中药方剂最有可能是最佳治疗措施(P<0.05);在改善蒙特利尔认知评估量表(MoCA)评分方面,针刺联合中药方剂最有可能是最佳治疗措施(P<0.05);在改善临床治疗总有效率方面,针刺联合重复经颅磁刺激最有可能是最佳治疗措施(P<0.05)。
针刺联合中药方剂可能是 PSCI 治疗中最有效的干预措施。