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贲门失弛缓症的治疗。机器人手术还是腹腔镜手术?

Achalasia Treatment. Robotic Approach or Laparoscopy?

出版信息

Chirurgia (Bucur). 2023 Jun;118(3):272-280. doi: 10.21614/chirurgia.2023.v.118.i.3.p.272.

DOI:10.21614/chirurgia.2023.v.118.i.3.p.272
PMID:37480353
Abstract

Nowadays the question persists whether to choose the endoscopic or surgical method as the first treatment of choice for achalasia. Another debate topic is about the differences between the outcomes of the two approaches of minimally invasive surgical treatment and their feasibility. Material and This retrospective observational study included 193 patients with achalasia treated between 2008 and 2021. The patients were divided into 2 groups (A and B): 152 with minimally invasive heller myotomy (HM), and 41 with pneumatic dilation (PD). Patients surgically treated were then subdivided into robotic group (RG) and laparoscopic group (LG). The recurrence rate was significantly higher in PD group (Ã?2 = 16.81, DF = 1, p 0.0001), with a success rate of 63,4%, comparing with 92,7% in HM group. No significant difference was obtained between the 2 groups concerning symptom relief on patients successfully treated. The success rate was comparable between the robotic and laparoscopic groups (p = 1). Significant difference was obtained in length of hospital stay between the 2 groups, with a mean of 4.78 +-1.59 days in the RG and, respectively, 5.52 +-2.1 days in the LG (t = 2.40, DF = 124.34, p = 0.0177). Postprocedural esophagitis rates were higher in patients with no fundoplication (6 out of 37 - 16.2%) and in patients treated with pneumatic dilation (4 out of 26 - 15.4%) than in patients with fundoplication (4 out of 46 - 8.5%). Conclusion: The present study indicates that surgery may be a better choice in fit patients for the treatment of achalasia. The procedure has a better success rate, even if the long-term outcomes are comparable in patients successfully treated. The success rate and long-term results were comparable between laparoscopy and robotic surgery.

摘要

目前,仍存在争议,即究竟应选择内镜治疗还是手术治疗作为贲门失弛缓症的首选治疗方法。另一个争论点是微创治疗的两种方法的结果及其可行性之间的差异。

本回顾性观察研究纳入了 2008 年至 2021 年间治疗的 193 例贲门失弛缓症患者。患者分为 2 组(A 组和 B 组):152 例行微创海勒肌切开术(HM),41 例行气囊扩张术(PD)。然后将手术治疗的患者进一步分为机器人组(RG)和腹腔镜组(LG)。PD 组的复发率明显更高(Ã?2 = 16.81,DF = 1,p 0.0001),成功率为 63.4%,而 HM 组的成功率为 92.7%。在成功治疗的患者中,两组间症状缓解率无显著差异。机器人组和腹腔镜组的成功率相当(p = 1)。两组间的住院时间有显著差异,RG 组平均为 4.78 +-1.59 天,LG 组分别为 5.52 +-2.1 天(t = 2.40,DF = 124.34,p = 0.0177)。无胃底折叠术的患者(37 例中有 6 例,16.2%)和行气囊扩张术的患者(26 例中有 4 例,15.4%)术后食管炎发生率高于行胃底折叠术的患者(46 例中有 4 例,8.5%)。

结论

本研究表明,对于适合手术的患者,手术可能是治疗贲门失弛缓症的更好选择。该手术的成功率更高,即使在成功治疗的患者中,长期结果也相似。腹腔镜手术和机器人手术的成功率和长期结果相当。

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引用本文的文献

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Robotic versus laparoscopic heller myotomy for esophageal achalasia: an updated systematic review and meta-analysis.机器人辅助与腹腔镜下贲门失弛缓症肌切开术的比较:一项更新的系统评价和荟萃分析。
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