Department of Chemistry, College of Arts and Science, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Medical Surgical Nursing Department, King Khalid University, Almahala, Saudi Arabia.
Crit Rev Anal Chem. 2024;54(8):3252-3268. doi: 10.1080/10408347.2023.2238059. Epub 2023 Jul 22.
Veterinary pharmaceuticals have been recently recognized as newly emerging environmental contaminants. Indeed, because of their uncontrolled or overused disposal, we are now facing undesirable amounts of these constituents in foodstuff and its related human health concerns. In this context, developing a well-organized environmental and foodstuff screening toward antibiotic levels is of paramount importance to ensure the safety of food products as well as human health. In this case, with the development and progress of electric/photo detecting, nanomaterials, and nucleic acid aptamer technology, their incorporation-driven evolving electrochemiluminescence aptasensing strategy has presented the hopeful potentials in identifying the residual amounts of different antibiotics toward sensitivity, economy, and practicality. In this context, we reviewed the up-to-date development of ECL aptasensors with aptamers as recognition elements and nanomaterials as the active elements for quantitative sensing the residual antibiotics in foodstuff and agriculture-related matrices, dissected the unavoidable challenges, and debated the upcoming prospects.
兽用药品最近已被确认为新出现的环境污染物。事实上，由于其处置方式不受控制或过度使用，我们现在正面临着食品中这些成分的数量过多，以及与之相关的人类健康问题。在这种情况下，针对抗生素水平制定组织良好的环境和食品筛查至关重要，以确保食品安全和人类健康。在这种情况下，随着电/光检测、纳米材料和核酸适体技术的发展和进步，基于它们的引入而不断发展的电化学发光适体传感策略在识别不同抗生素的残留量方面表现出了有希望的潜力，具有灵敏度高、经济性和实用性强的特点。在此背景下，我们综述了以适体作为识别元件，纳米材料作为活性元件的电化学发光适体传感器的最新发展，剖析了不可避免的挑战，并讨论了即将到来的前景。
