Singh Priyanka, Ali Saba Naaz, Zaheer Sufian, Singh Mukul
Department of Pathology, VMMC, and Safdarjang Hospital, New Delhi, India.
Department of Pathology, VMMC, and Safdarjang Hospital, New Delhi, India.
Pathol Res Pract. 2023 Aug;248:154691. doi: 10.1016/j.prp.2023.154691. Epub 2023 Jul 14.
The interstitial lung diseases (ILDs) are a large, heterogeneous group of several hundred generally rare pulmonary pathologies, which show injury, inflammation and/or scarring in the lung. Although the aetiology of these disorders remains largely unknown, various cellular mechanisms have an important role in pathogenesis of fibrosis on the background of occupational, environmental and genetic factors. We have tried to provide new insights into the interactions and cellular contributions, analysing the roles of various cells in the pathogenesis of idiopathic pulmonary fibrosis.
间质性肺疾病（ILDs）是一大类、异质性的数百种通常罕见的肺部疾病，其在肺部表现出损伤、炎症和/或瘢痕形成。尽管这些疾病的病因在很大程度上仍不清楚，但在职业、环境和遗传因素的背景下，各种细胞机制在纤维化的发病机制中发挥着重要作用。我们试图通过分析各种细胞在特发性肺纤维化发病机制中的作用，为相互作用和细胞贡献提供新的见解。
