de Leeuw P W, Birkenhäger W H
Nephron. 1986;44 Suppl 1:5-7. doi: 10.1159/000184036.
In this paper several aspects of the evaluation of renal perfusion by means of the xenon-133 washout technique are reviewed. Although the method requires arterial catheterization, and is difficult to carry out in the face of far-advanced renal artery stenosis, in many patients it may provide useful information on the intrarenal hemodynamic pattern. In patients with renal artery stenosis the percentage of total flow perfusing the rapid compartment (= outer cortex) is maintained, but absolute flow in that compartment is reduced to a variable degree. It is suggested that this reflects recruitment of fast-flow nephrons in response to a fall in perfusion pressure.
本文回顾了通过氙-133洗脱技术评估肾灌注的几个方面。尽管该方法需要进行动脉插管，并且在严重肾动脉狭窄的情况下难以实施，但在许多患者中，它可能提供有关肾内血流动力学模式的有用信息。在肾动脉狭窄患者中，灌注快速区室（即外皮质）的总血流量百分比保持不变，但该区域的绝对血流量会不同程度地减少。有人认为，这反映了快速流动肾单位对灌注压下降的代偿性募集。
