正常和灌注不足犬肾中氙-133洗脱曲线与放射性微球分布的比较。

Comparison of the xenon-133 washout curve and radioactive microsphere distribution in the normal and hypoperfused dog kidney.

作者信息

Huland H, Leichtweiss H P, Schröder H, Jeschkies R

出版信息

Urol Int. 1982;37(3):205-12. doi: 10.1159/000280818.

Abstract

Intrarenal blood flow distribution was measured in normal and hypoperfused dog kidneys by xenon-133 washout measurement in one kidney vary slightly in contrast to those done in different kidneys. In normal kidneys the ratio of compartment I (CI) flow to whole renal flow -- i.e., the CI fraction--as measured by the xenon-133 washout curves is almost identical with the distribution of radioactive microspheres in the outer three-fourths of renal cortex (= SI). In hypoperfused dog kidneys, both techniques demonstrate redistribution of blood flow due to reduction predominantly in the CI fraction and the SI zone. The CI fraction is smaller than the microsphere distribution in zone SI in 3 of 5 hypoperfused kidneys. This is explained on the basis of increased cortical flow inhomogeneity in the hypoperfused kidneys.

摘要

通过对一侧肾脏进行氙-133洗脱测量，来测定正常和灌注不足犬肾的肾内血流分布。一侧肾脏的测量结果与不同肾脏的测量结果相比略有差异。在正常肾脏中，通过氙-133洗脱曲线测量的I区（CI）血流与全肾血流之比，即CI分数，几乎与放射性微球在肾皮质外四分之三区域（=SI）的分布相同。在灌注不足的犬肾中，两种技术均显示由于主要是CI分数和SI区减少导致血流重新分布。在5个灌注不足的肾脏中，有3个肾脏的CI分数小于SI区的微球分布。这是基于灌注不足肾脏中皮质血流不均匀性增加来解释的。