From the Department of Diagnostic and Interventional Radiology.
Division of Oncology, The University of Texas Health Science Center at Houston, Houston, TX.
Clin Nucl Med. 2023 Sep 1;48(9):e452-e454. doi: 10.1097/RLU.0000000000004768. Epub 2023 Jul 22.
68 Ga-DOTATATE PET/CT is a highly sensitive and specific imaging modality in detecting neuroendocrine tumors. False-positive DOTATATE uptake poses diagnostic challenges. False-positive uptake in a uterine fibroid is the third most common location. We report the case of a 45-year-old woman with clinical concern for possible neuroendocrine tumor showing moderate focal DOTATATE uptake, which was initially thought of to be localized to mesentery on PET/CT images but was subsequently localized to a subserosal uterine fibroid following MRI. Patient underwent hysterectomy, further confirming that the uterine myometrial uptake is within the subserosal fibroid.
68Ga-DOTATATE PET/CT 是一种高度敏感和特异的成像方式,可用于检测神经内分泌肿瘤。假阳性 DOTATATE 摄取会带来诊断挑战。在子宫肌瘤中,假阳性摄取是第三常见的部位。我们报告了一例 45 岁女性,临床怀疑可能患有神经内分泌肿瘤,显示出中度局灶性 DOTATATE 摄取,最初认为在 PET/CT 图像上定位于肠系膜,但随后在 MRI 上定位于子宫浆膜下肌瘤。患者接受了子宫切除术,进一步证实子宫肌层摄取位于浆膜下肌瘤内。