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轻度认知障碍和轻度阿尔茨海默病中的医疗资源使用与社会成本

Health Care Resource Use and Social Costs in Mild Cognitive Impairment and Mild Alzheimer's Disease.

作者信息

Takechi Hajime, Yoshino Hiroshi

机构信息

Department of Geriatrics and Cognitive Disorders, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.

出版信息

J Alzheimers Dis Rep. 2023 Jul 14;7(1):731-738. doi: 10.3233/ADR-230032. eCollection 2023.

DOI:10.3233/ADR-230032
PMID:37483328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10357114/
Abstract

BACKGROUND

As the number of patients with dementia increases, so do the social costs. In recent years, attempts have been made to reduce risk to be dementia and treat it from the early stages of the disease, making it important to estimate the costs of the early stages.

OBJECTIVE

To estimate the medical and social costs of the early stages of Alzheimer's disease (AD), which include mild cognitive impairment (MCI) due to AD and mild AD.

METHODS

Questionnaires were used to obtain basic information (e.g., age, cognitive function) and medical costs, social care costs, family caregiver medical costs, and family caregiver informal care costs from patients with MCI due to AD or mild AD who were attending a memory clinic. A comparison was then conducted between these two groups.

RESULTS

Patients with mild AD had higher total costs, patient medical costs, patient social care costs, and family caregiver informal care costs than did patients with MCI; however, only patient medical costs were significantly different ( = 0.022). A detailed analysis of patient medical costs revealed that anti-dementia drug treatment costs were significantly higher in patients with mild AD ( <  0.001).

CONCLUSION

Compared with patients with mild AD, those with MCI may have lower patient and family caregiver costs. As it is important to reduce social costs through risk reduction and therapeutic interventions from the early stages of AD, the present findings could help estimate the social costs and verify the cost-effectiveness of early interventions for AD.

摘要

背景

随着痴呆症患者数量的增加,社会成本也在上升。近年来,人们一直在尝试降低患痴呆症的风险并在疾病早期进行治疗,因此估计早期阶段的成本变得很重要。

目的

估计阿尔茨海默病(AD)早期阶段的医疗和社会成本,包括由AD导致的轻度认知障碍(MCI)和轻度AD。

方法

通过问卷调查从就诊于记忆门诊的由AD导致的MCI或轻度AD患者中获取基本信息(如年龄、认知功能)以及医疗成本、社会护理成本、家庭照顾者医疗成本和家庭照顾者非正式护理成本。然后对这两组进行比较。

结果

轻度AD患者的总成本、患者医疗成本、患者社会护理成本和家庭照顾者非正式护理成本均高于MCI患者;然而,只有患者医疗成本存在显著差异(=0.022)。对患者医疗成本的详细分析显示,轻度AD患者的抗痴呆药物治疗成本显著更高(<0.001)。

结论

与轻度AD患者相比,MCI患者的患者和家庭照顾者成本可能更低。由于从AD早期阶段通过降低风险和治疗干预来降低社会成本很重要,本研究结果有助于估计社会成本并验证AD早期干预的成本效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca1/10357114/66625e64b6e1/adr-7-adr230032-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca1/10357114/66625e64b6e1/adr-7-adr230032-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca1/10357114/66625e64b6e1/adr-7-adr230032-g001.jpg

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