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喘息作为儿童弥漫性泛细支气管炎与哮喘鉴别诊断的重要体格检查发现:一例报告

Squawks as an important physical finding for differentiation of diffuse panbronchiolitis from asthma in children: A case report.

作者信息

Okumura Hisatoshi, Kawashima Atsushi, Hanamoto Akiko

机构信息

Division of General Internal Medicine Fukuchiyama City Hospital Fukuchiyama-shi Japan.

Independent Resercher Kyoto Japan.

出版信息

J Gen Fam Med. 2023 Jun 22;24(4):261-263. doi: 10.1002/jgf2.635. eCollection 2023 Jul.

DOI:10.1002/jgf2.635
PMID:37484129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10357090/
Abstract

Diffuse panbronchiolitis (DPB) is an idiopathic chronic inflammatory pulmonary disease clinically characterized by cough, sputum, and chronic sinusitis. Although the average age of onset is 40 years, DPB occasionally occurs in children and is often misdiagnosed as asthma. Long-term therapy with macrolide antibiotics significantly improves survival in DPB. Herein, we report the case of a 16-year-old man who had been treated for asthma and was referred to our department as transition from the Department of Pediatrics. Adequate auscultation to detect squawks and history taking of purulent sputum led to the correct diagnosis and appropriate treatment, which improved his quality of life.

摘要

弥漫性泛细支气管炎(DPB)是一种特发性慢性炎症性肺疾病,临床特征为咳嗽、咳痰和慢性鼻窦炎。尽管平均发病年龄为40岁,但DPB偶尔也会发生在儿童中,且常被误诊为哮喘。长期使用大环内酯类抗生素治疗可显著提高DPB患者的生存率。在此,我们报告一例16岁男性患者,他曾接受哮喘治疗,后从儿科转入我科。通过充分听诊以检测粗啰音和询问脓性痰病史得以正确诊断并进行恰当治疗,从而改善了他的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0df/10357090/ef7e52378726/JGF2-24-261-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0df/10357090/ef7e52378726/JGF2-24-261-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0df/10357090/ef7e52378726/JGF2-24-261-g002.jpg

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本文引用的文献

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Three cases of diffuse panbronchiolitis in children with a past history of difficult-to-treat bronchial asthma: A case report from a single medical facility.三例既往有难治性支气管哮喘病史儿童的弥漫性泛细支气管炎:来自单一医疗机构的病例报告
Allergol Int. 2020 Jul;69(3):468-470. doi: 10.1016/j.alit.2020.02.007. Epub 2020 Mar 23.
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中国西部一名儿童弥漫性泛细支气管炎的成功治疗:病例报告
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