Toldi J, Farkas Z, Fehér O, Dames W, Kása P, Gyurkovits K, Joó F, Wolff J R
Neurosci Lett. 1986 Aug 15;69(1):19-24. doi: 10.1016/0304-3940(86)90407-6.
The possible effect of sodium bromide (NaBr) (a substance with known inhibitory action on synaptic transmission) was studied on synapse formation with foreign nerves, implanted into the superior cervical ganglion of adult rats. It was found that in spite of the presence of preganglionic nerve supply, both implanted nerves (n.XII and n.X, respectively) were enabled to establish functional synapses with the principal ganglion cells in NaBr-treated animals. In contrast, synapse formation was almost absent in ganglia of sodium chloride drinking (control) rats with intact preganglionic nerve supply. This effect of NaBr is considered to be analogous to that of GABA, whose promoting action on synaptogenesis in adult rat superior cervical ganglion has been previously described.
研究了溴化钠（NaBr）（一种已知对突触传递有抑制作用的物质）对植入成年大鼠颈上神经节的外来神经突触形成的可能影响。结果发现，尽管存在节前神经供应，但在接受NaBr处理的动物中，两条植入神经（分别为第十二对脑神经和第十对脑神经）均能与主要神经节细胞建立功能性突触。相比之下，饮用氯化钠（对照）的大鼠神经节中，节前神经供应完整，但几乎没有突触形成。NaBr的这种作用被认为与γ-氨基丁酸（GABA）的作用类似，此前已有研究描述过GABA对成年大鼠颈上神经节突触形成的促进作用。
