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γ-氨基丁酸或溴化钠诱导培养的小鼠神经母细胞瘤细胞神经突的可塑性:一项定量研究。

GABA or sodium-bromide-induced plasticity of neurites of mouse neuroblastoma cells in culture. A quantitative study.

作者信息

Eins S, Spoerri P E, Heyder E

出版信息

Cell Tissue Res. 1983;229(2):457-60. doi: 10.1007/BF00214987.

DOI:10.1007/BF00214987
PMID:6850757
Abstract

Differentiated C1300 mouse neuroblastoma cells were treated with 10(-4)-10(6) M gamma-aminobutyric acid (GABA) and/or sodium bromide (NaBr) for 2 days and then fixed. Quantitative studies revealed an increase in the length and branching of the processes, as well as an increase in the number of cells when compared to the controls. It is suggested that the above changes contribute to the augmentation of specialized contacts between cells and processes as well as the further maturation of the primitive stages of synaptogenesis as discussed.

摘要

将分化的C1300小鼠神经母细胞瘤细胞用10⁻⁴ - 10⁶ M的γ-氨基丁酸(GABA)和/或溴化钠(NaBr)处理2天,然后固定。定量研究显示,与对照组相比,细胞突起的长度和分支增加,细胞数量也增加。上述变化被认为有助于增加细胞与突起之间的特殊接触,以及如所讨论的突触发生原始阶段的进一步成熟。

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GABA or sodium-bromide-induced plasticity of neurites of mouse neuroblastoma cells in culture. A quantitative study.γ-氨基丁酸或溴化钠诱导培养的小鼠神经母细胞瘤细胞神经突的可塑性:一项定量研究。
Cell Tissue Res. 1983;229(2):457-60. doi: 10.1007/BF00214987.
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本文引用的文献

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Effect of GABA-administration on murine neuroblastoma cells in culture. I. Increased membrane dynamics and formation of specialized contacts.
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Morphological changes induced by sodium bromide in murine neuroblastoma cells in vitro.溴化钠在体外诱导小鼠神经母细胞瘤细胞发生的形态学变化。
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